ReviewJournal of intensive care2022
Body position for preventing ventilator-associated pneumonia for critically ill patients: a systematic review and network meta-analysis.
Review in Journal of intensive care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05953649 (Effect of Early Extracorporeal Diaphragm Pacing (EDP) Combined With Tilt Table Verticalization (TTV) on Diaphragm Function in Critically Ill Patients With Mechanical Ventilation), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Early Extracorporeal Diaphragm Pacing (EDP) Combined With Tilt Table Verticalization (TTV) on Diaphragm Function in Critically Ill Patients With Mechanical Ventilation: a Randomized Controlled Trial.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2025: post-resuscitation care.Intensive care medicine · 2025Guideline
- Effect of Continuous Lateral Rotation Therapy on Clinical Outcomes in Mechanically Ventilated Critically Ill Adults.Respiratory care · 2024Pooled it
- Guideline on positioning and early mobilisation in the critically ill by an expert panel.Intensive care medicine · 2024Guideline
- Physiology of body lateralization on regional lung ventilation and lung volumes in healthy subjects: Within-subjects design.PloS one · 2025Trial
- Consensus statement on the use of standardized early mobilization in pediatric patients admitted to pediatric intensive care units in Italy.European journal of pediatrics · 2026Review
- Host, Pathogen, and Pulmonary Anatomy in Pneumonia: An Integrated Imaging and Clinical Perspective.Diagnostics (Basel, Switzerland) · 2026Review
- Carbapenem resistance and hypervirulence iniScience · 2026Review
- The Effect of Body Position on Responses to Rapid Bilateral Anterolateral Magnetic Phrenic Nerve Stimulation in Healthy Humans (PosiStim).Respiration; international review of thoracic diseases · 2026Article
- A potential bundle for preventing ventilator-associated pneumonia in the emergency department: A narrative review.The Journal of international medical research · 2026Article
- Saudi Guideline for Mechanical Ventilation in Adults.Saudi journal of medicine & medical sciences · 2026Article
- Lung ultrasound-guided positioning strategy for the prevention of ventilator-associated pneumonia in neonates.Frontiers in pediatrics · 2026Article
- Effects of the beach chair position on respiratory mechanics in patients with chronic obstructive pulmonary disease hospitalized in intensive care unit.BMC anesthesiology · 2025Article
- Article
- Exploring Early Mobilization Practices in Adult Intensive Care Units in Jordan: A Cross-Sectional Survey.Journal of multidisciplinary healthcare · 2025Article
- Impact of proactive risk-prevention nursing interventions on the recovery of ICU patients with ventilator-associated pneumonia.Frontiers in medicine · 2025Article
- Preventing ventilator-associated pneumonia non-pharmacologically.Intensive care medicine · 2024Article
- PEEP Titration Is Markedly Affected by Trunk Inclination in Mechanically Ventilated Patients with COVID-19 ARDS: A Physiologic, Cross-Over Study.Journal of clinical medicine · 2023Article
- Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective, observational study.Scientific reports · 2023Observational
- Article
- Epidemiology of ventilator-associated pneumonia in ICU COVID-19 patients: an alarming high rate of multidrug-resistant bacteria.Journal of anesthesia, analgesia and critical care · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe evidence about the best body position to prevent ventilator-associated pneumonia (VAP) is unclear. The aim of this study was to know what the best body position is to prevent VAP, shorten the length of intensive care unit (ICU) and hospital stay, and reduce mortality among patients undergoing mechanical ventilation (MV).
methodsWe performed a network meta-analysis of randomized controlled trials including intubated patients undergoing MV and admitted to an ICU. The assessed interventions were different body positions (i.e., lateral, prone, semi-recumbent) or alternative degrees of positioning in mechanically ventilated patients.
resultsSemi-recumbent and prone positions showed a risk reduction of VAP incidence (RR: 0.38, 95% CI: 0.25-0.52) and mortality (RR: 0.70, 95% CI: 0.50-0.91), respectively, compared to the supine position. The ranking probabilities and the surface under the cumulative ranking displayed as the first best option of treatment the semi-recumbent position to reduce the incidence of VAP (71.4%), the hospital length of stay (68.9%), and the duration of MV (67.6%); and the prone position to decrease the mortality (89.3%) and to reduce the ICU length of stay (59.3%).
conclusionsCautiously, semi-recumbent seems to be the best position to reduce VAP incidence, hospital length of stay and the duration of MV. Prone is the most effective position to reduce the risk of mortality and the ICU length of stay, but it showed no effect on the VAP incidence. Registration PROSPERO CRD42021247547.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.