Evidence map›Paper›PMID 35193688›Full record

ReviewJournal of intensive care2022

Body position for preventing ventilator-associated pneumonia for critically ill patients: a systematic review and network meta-analysis.

Diana P Pozuelo-Carrascosa, Ana Isabel Cobo-Cuenca, Juan Manuel Carmona-Torres, Jose Alberto Laredo-Aguilera, Esmeralda Santacruz-Salas, Ruben Fernandez-Rodriguez

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Journal of intensive care, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05953649 (Effect of Early Extracorporeal Diaphragm Pacing (EDP) Combined With Tilt Table Verticalization (TTV) on Diaphragm Function in Critically Ill Patients With Mechanical Ventilation), which is not on this map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05953649 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Early Extracorporeal Diaphragm Pacing (EDP) Combined With Tilt Table Verticalization (TTV) on Diaphragm Function in Critically Ill Patients With Mechanical Ventilation: a Randomized Controlled Trial.

TypeinterventionalSponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityRan2023 to 2024Enrolled90ConditionsEarly Mobilization, Critically Ill, Mechanical Ventilation, Diaphragm DysfunctionArmsExtracorporeal Diaphragm Pacing, Tilt Table Verticalization, Conventional Physiotherapy
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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  10. Saudi Guideline for Mechanical Ventilation in Adults.Saudi journal of medicine & medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Diana P Pozuelo-CarrascosaFaculty of Physiotherapy and Nursing of Toledo, Department of Nursing, Physiotherapy and Occupational Therapy, University of Castilla-La Mancha, 45005, Toledo, Spain.ORCID http://orcid.org/0000-0002-0527-5498
Ana Isabel Cobo-CuencaFaculty of Physiotherapy and Nursing of Toledo, Department of Nursing, Physiotherapy and Occupational Therapy, University of Castilla-La Mancha, 45005, Toledo, Spain. anaisabel.cobo@uclm.es.ORCID http://orcid.org/0000-0001-7873-3835
Juan Manuel Carmona-TorresFaculty of Physiotherapy and Nursing of Toledo, Department of Nursing, Physiotherapy and Occupational Therapy, University of Castilla-La Mancha, 45005, Toledo, Spain.ORCID https://orcid.org/0000-0002-7781-872X
Jose Alberto Laredo-AguileraFaculty of Physiotherapy and Nursing of Toledo, Department of Nursing, Physiotherapy and Occupational Therapy, University of Castilla-La Mancha, 45005, Toledo, Spain.ORCID http://orcid.org/0000-0002-3661-3584
Esmeralda Santacruz-SalasFaculty of Physiotherapy and Nursing of Toledo, Department of Nursing, Physiotherapy and Occupational Therapy, University of Castilla-La Mancha, 45005, Toledo, Spain.ORCID http://orcid.org/0000-0002-4249-3179
Ruben Fernandez-RodriguezHealth and Social Research Center (CESS), University of Castilla-La Mancha, Cuenca, Spain.ORCID http://orcid.org/0000-0001-7584-7642
Instituto Maimónides de Investigación Biomédica de Córdoba · ESUniversity of Castilla-La Mancha · ES

Funding

Fondo Europeo de Desarrollo Regional (FEDER) This research was funded by a grant from the European Regional Development Fund (ERDF) [Fondo Europeo de Desarrollo Regional (FEDER), (DOCM 27/01/2021)]
6 · The paper itself

Abstract

backgroundThe evidence about the best body position to prevent ventilator-associated pneumonia (VAP) is unclear. The aim of this study was to know what the best body position is to prevent VAP, shorten the length of intensive care unit (ICU) and hospital stay, and reduce mortality among patients undergoing mechanical ventilation (MV).

methodsWe performed a network meta-analysis of randomized controlled trials including intubated patients undergoing MV and admitted to an ICU. The assessed interventions were different body positions (i.e., lateral, prone, semi-recumbent) or alternative degrees of positioning in mechanically ventilated patients.

resultsSemi-recumbent and prone positions showed a risk reduction of VAP incidence (RR: 0.38, 95% CI: 0.25-0.52) and mortality (RR: 0.70, 95% CI: 0.50-0.91), respectively, compared to the supine position. The ranking probabilities and the surface under the cumulative ranking displayed as the first best option of treatment the semi-recumbent position to reduce the incidence of VAP (71.4%), the hospital length of stay (68.9%), and the duration of MV (67.6%); and the prone position to decrease the mortality (89.3%) and to reduce the ICU length of stay (59.3%).

conclusionsCautiously, semi-recumbent seems to be the best position to reduce VAP incidence, hospital length of stay and the duration of MV. Prone is the most effective position to reduce the risk of mortality and the ICU length of stay, but it showed no effect on the VAP incidence. Registration PROSPERO CRD42021247547.

Indexed as

Body positionProneSemi-recumbentSupineVentilator-associated pneumonia

Identifiers

PMID35193688
PMCPMC8864849
OpenAlexW4213373282

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.