Evidence map›Paper›PMID 35193524›Full record

ReviewBMC ophthalmology2022

Is dry eye disease the same in young and old patients? A narrative review of the literature.

Stefano Barabino

Open access · goldAbstract readReview
In one paragraph

Review in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 46 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Pregnancy and Dry Eye Syndrome: A Review for Clinical Practice.International journal of molecular sciences · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Development andNanoscale advances · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Consumption ofInternational journal of molecular sciences · 2024
    Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Stefano BarabinoOcular Surface & Dry Eye Center, ASST Fatebenefratelli-Sacco, Ospedale L. Sacco, Università di Milano, via GB Grassi, 57, 20157, Milan, Italy. stebarabi@gmail.com.ORCID http://orcid.org/0000-0002-6317-8848
ASST Fatebenefratelli Sacco · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advanced age is one of the most evident risk factors for dry eye disease (DED), with male/female sex, chronic drug consumption, and prolonged device use. This article aims to review the literature about the changes of the ocular surface associated with DED in the elderly and patients < 40 years. The pathophysiologic changes of the ocular surface responsible for eye dryness are linked with inflammation and neurosensory abnormalities and may occur with a different feature in young patients compared with elders. Peculiar treatment strategies may be needed for young and older subjects with DED.

Indexed as

Dry Eye SyndromesTearsAgedEyeFemaleHumansInflammationMaleBlinkDry eye diseaseOcular surfaceTear film

Identifiers

PMID35193524
PMCPMC8861619
OpenAlexW4212894192

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.