Evidence map›Paper›PMID 35193508›Full record

ArticleBMC neurology2022

Spinal cysticercosis: a rare cause of myelopathy.

Chenlong Yang, Tie Liu, Jian Wu, Jingcheng Xie, Tao Yu, Wenqing Jia, Jun Yang, Yulun Xu

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Chenlong Yang *Department of Neurosurgery, Peking University Third Hospital, Haidian District, Beijing, China.
Tie Liu *Department of Neurosurgery, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jian WuDepartment of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, USA.
Jingcheng XieDepartment of Neurosurgery, Peking University Third Hospital, Haidian District, Beijing, China.
Tao YuDepartment of Neurosurgery, Peking University Third Hospital, Haidian District, Beijing, China.
Wenqing JiaDepartment of Neurosurgery, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Jun YangDepartment of Neurosurgery, Peking University Third Hospital, Haidian District, Beijing, China. yangjbysy@bjmu.edu.cn.ORCID http://orcid.org/0000-0002-8099-2796
Yulun XuDepartment of Neurosurgery, China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China. xuhuxi@sina.cn.
Peking University · CNCapital Medical University · CNStanford University · US

Funding

National Natural Science Foundation of China 81901202
6 · The paper itself

Abstract

backgroundNeurocysticercosis is a neuroinfectious disease caused by the larval stage of the tapeworm Taenia solium. Isolated spinal cysticercosis is rare, with limited cases having been reported in the literature. This entity poses great diagnostic and therapeutic challenges.

methodsThis retrospective study included seven patients pathologically diagnosed with spinal cysticercosis. The clinical manifestations, radiological features on magnetic resonance imaging (MRI), treatment, and outcomes were analyzed.

resultsThis case series consisted of four male and three female patients, with an average age of 34.9 ± 10.9 years. Clinically, six patients manifested with localization-related myelopathy. There were four solid lesions, one cystic-solid lesion, and three cystic lesions. The solid and cystic-solid lesions showed characteristic MRI features: 1) within the lesion, there was a mural nodule with isointensity on T1WI and iso- to hyperintensity on T2WI; 2) the signals at the periphery of the mural nodule were variable, ranging from hypointense to hyperintense on T2WI; and 3) ring-like or cyst wall enhancement could be present, and dot-like enhancement could be noted in the mural nodule. Complete resection of the responsible lesion was achieved in all patients, and oral albendazole was administered in a patient with one more suspected homologous lesion. After a mean follow-up period of 56.7 ± 35.1 months, the patient's symptoms mostly regressed.

conclusionSpinal cysticercosis is an extremely rare cause of myelopathy. Characteristic MRI features can facilitate preoperative diagnosis. Clinicians should be aware of this entity, and it should be included in the differential diagnosis of myelopathy.

Indexed as

CysticercosisNeurocysticercosisSpinal Cord DiseasesAdultFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesSpineYoung AdultCysticercosisMyelopathyNeurocysticercosisParasitic infectionTaenia solium

Identifiers

PMID35193508
PMCPMC8862344
OpenAlexW4213234221

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.