Evidence map›Paper›PMID 35193444›Full record

ArticleJournal of enzyme inhibition and medicinal chemistry2022

Thio- and selenosemicarbazones as antiprotozoal agents against

Alexandra Ibáñez-Escribano, Cristina Fonseca-Berzal, Mónica Martínez-Montiel, Manuel Álvarez-Márquez, María Gómez-Núñez, Manuel Lacueva-Arnedo, Teresa Espinosa-Buitrago, Tania Martín-Pérez, José Antonio Escario, Penélope Merino-Montiel and 4 more

Abstract read
In one paragraph

Article in Journal of enzyme inhibition and medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  3. IntegratedPharmaceuticals (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alexandra Ibáñez-EscribanoUnidad de Parasitología, Departamento de Microbiología y Parasitología, Facultad de Farmacia, Madrid, Spain.
Cristina Fonseca-BerzalUnidad de Parasitología, Departamento de Microbiología y Parasitología, Facultad de Farmacia, Madrid, Spain.
Mónica Martínez-MontielFacultad de Ciencias Químicas, Ciudad Universitaria, Benemérita Universidad Autónoma de Puebla, Puebla, México.
Manuel Álvarez-MárquezDepartamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Sevilla, Spain.
María Gómez-NúñezEscuela Politécnica Superior, Universidad de Sevilla, Sevilla, Spain.
Manuel Lacueva-ArnedoUnidad de Parasitología, Departamento de Microbiología y Parasitología, Facultad de Farmacia, Madrid, Spain.
Teresa Espinosa-BuitragoUnidad de Parasitología, Departamento de Microbiología y Parasitología, Facultad de Farmacia, Madrid, Spain.
Tania Martín-PérezDepartamento de Biomedicina y Biotecnología, Facultad de Farmacia, Universidad de Alcalá, Alcalá de Henares, Madrid, Spain.
José Antonio EscarioUnidad de Parasitología, Departamento de Microbiología y Parasitología, Facultad de Farmacia, Madrid, Spain.
Penélope Merino-MontielFacultad de Ciencias Químicas, Ciudad Universitaria, Benemérita Universidad Autónoma de Puebla, Puebla, México.
Sara Montiel-SmithFacultad de Ciencias Químicas, Ciudad Universitaria, Benemérita Universidad Autónoma de Puebla, Puebla, México.
Alicia Gómez-BarrioUnidad de Parasitología, Departamento de Microbiología y Parasitología, Facultad de Farmacia, Madrid, Spain.
Óscar LópezDepartamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Sevilla, Spain.
José G Fernández-BolañosDepartamento de Química Orgánica, Facultad de Química, Universidad de Sevilla, Sevilla, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Herein, we report the preparation of a panel of Schiff bases analogues as antiprotozoal agents by modification of the stereoelectronic effects of the substituents on N-1 and N-4 and the nature of the chalcogen atom (S, Se). These compounds were evaluated towards

Indexed as

Antiprotozoal AgentsDose-Response Relationship, DrugMolecular StructureParasitic Sensitivity TestsSemicarbazonesStructure-Activity RelationshipTrichomonas vaginalisTrypanosoma cruziAntiprotozoal AgentsSemicarbazonesantiprotozoal agentsMoAthio(seleno)semicarbazonesTrichomonas vaginalisTrypanosoma cruziunspecific cytotoxicity

Identifiers

PMID35193444
PMCPMC8881069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.