Evidence map›Paper›PMID 35193387›Full record

ArticleJournal of the Royal Society, Interface2022

Fractality of tics as a quantitative assessment tool for Tourette syndrome.

Payton Beeler, Nicholas O Jensen, Soyoung Kim, Amy Robichaux-Viehoever, Bradley L Schlaggar, Deanna J Greene, Kevin J Black, Rajan K Chakrabarty

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Automated Quantification of Eye Tics Using Computer Vision and Deep Learning Techniques.Movement disorders : official journal of the Movement Disorder Society · 2024
    Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Payton BeelerCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St Louis, St Louis, MO 63110, USA.ORCID 0000-0003-4759-1461
Nicholas O JensenComputational and Systems Biology Program, Division of Biology and Biomedical Sciences, Washington University in St Louis, St Louis, MO 63110, USA.
Soyoung KimDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO 63130, USA.
Amy Robichaux-ViehoeverDepartment of Neurology, Washington University School of Medicine, St Louis, MO 63130, USA.
Bradley L SchlaggarKennedy Krieger Institute, Baltimore, MD 21205, USA.
Deanna J GreeneDepartment of Cognitive Science, University of California San Diego, La Jolla, CA 92093, USA.
Kevin J BlackDepartment of Psychiatry, Washington University School of Medicine, St Louis, MO 63130, USA.ORCID 0000-0002-6921-9567
Rajan K ChakrabartyCenter for Aerosol Science and Engineering, Department of Energy, Environmental and Chemical Engineering, Washington University in St Louis, St Louis, MO 63110, USA.ORCID 0000-0001-5753-9937

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Washington University Institute of Clinical and Translational Sciences (UL1)UL1RR024992 · NCRR · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2007 to 2011
$45.4M
Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
The New Tics Study: A Novel Approach to Pathophysiology and Cause of Tic DisordersR01MH104030 · NIMH · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J · 2017 to 2021
$3.3M
Longitudinal Study of Brain Imaging and Cognitive Markers of Tourette Syndrome in ChildrenR01MH118217 · NIMH · WASHINGTON UNIVERSITY · PI GREENE, DEANNA JACQUELYN · 2019 to 2025
$3.2M
Training New Investigators in Neuroimaging and in the Neuropsychiatry of MovementK24MH087913 · NIMH · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J · 2010 to 2014
$818k
PREDICTING OUTCOME IN CHILDREN WITH TIC DISORDERS USING NEUROIMAGING DATAK01MH104592 · NIMH · WASHINGTON UNIVERSITY · PI GREENE, DEANNA JACQUELYN · 2014 to 2018
$723k
PREDICTING OUTCOME IN CHILDREN WITH NEW-ONSET TICS USING NEUROIMAGING DATAR21NS091635 · NINDS · WASHINGTON UNIVERSITY · PI BLACK, KEVIN J, SCHLAGGAR, BRADLEY L · 2015 to 2016
$419k
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1 TR002345NCRR NIH HHS UL1 RR024992NIMH NIH HHS K01 MH104592NIMH NIH HHS K24 MH087913NIMH NIH HHS R01 MH104030NIMH NIH HHS R01 MH118217NINDS NIH HHS R21 NS091635
6 · The paper itself

Abstract

Tics manifest as brief, purposeless and unintentional movements or noises that, for many individuals, can be suppressed temporarily with effort. Previous work has hypothesized that the chaotic temporal nature of tics could possess an inherent fractality, that is, have neighbour-to-neighbour correlation at all levels of timescale. However, demonstrating this phenomenon has eluded researchers for more than two decades, primarily because of the challenges associated with estimating the scale-invariant, power law exponent-called the fractal dimension

Indexed as

TicsTourette SyndromeChildFractalsHumansSeverity of Illness IndexTreatment Outcomefractal‌provisional tic disorderticsTourette syndrome

Identifiers

PMID35193387
PMCPMC8864347

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.