Evidence map›Paper›PMID 35193333›Full record

ArticlePediatric endocrinology, diabetes, and metabolism2022

Ultrasonic evaluation of thelarche grading in 2-8-year-old obese girls suspected of precocious pubert.

Zahra Sadat Hosseini, Kobra Shiasi Arani, Alireza Moraveji, Hamid Reza Talari

Open access · diamondAbstract read
In one paragraph

Article in Pediatric endocrinology, diabetes, and metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zahra Sadat HosseiniDepartment of Radiology, Department of Radiology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
Kobra Shiasi AraniResearch Center of Biochemistry and Nutrition in Metabolic Disorder, Research Center of Biochemistry and Nutrition in Metabolic Disorder, Kashan University of Medical Science, Kashan, Iran.
Alireza MoravejiDepartment of Community Medicine, School of Medicine, Social Determinants of Health Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Hamid Reza TalariAnatomical Sciences Research Center, Anatomical Sciences Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran.
Kashan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe prevalence of obesity in children is increasing. In obese children, clinical examination alone is not sufficient to differentiate lipomastia from thelarche. The aim of this study was to investigate the frequency of true thelarche in obese girls suspected of precocious puberty. MATERIAL AND

methodsIn a cross-sectional study, 100 obese girls between the ages of 2 and 8 years were screened. Maturity stages were determined based on the Tanner scale in the questionnaire. Breast ultrasound was performed for all cases. Other uterine and ovarian laboratory tests, including blood tests to determine plasma levels of LH, FSH, oestradiol, and bone age, were also performed.

resultsIn ultrasonography examination of 80 children (80%), one breast was pubertal and in 72 people both breasts were pubertal in which ultrasonography of 78 children showed puberty of right breast and 74 children showed puberty of left breast. Twenty children showed bilateral lipomastia. In clinical examination, breasts of 18.9% children seemed lipoid, 35.8% children were seriously suspicious, and 45.3% children seemed pubescent. In pelvic ultrasound, the relationship between ovarian volume and breast ultrasound grade was significant, but uterine volume was not significantly related to breast ultrasound grade. Also, uterine volume with age at ultrasonography, bone age, birth height, left ovarian volume, right ovarian volume, right breast bud diameter, and left breast bud diameter were correlated.

conclusionsUltrasound can help obese or overweight children to differentiate between true thelarche and lipomastia. The study also found that most suspected children had true thelarche.

Indexed as

Pediatric ObesityPuberty, PrecociousChildChild, PreschoolCross-Sectional StudiesFemaleHumansUltrasonicsUltrasonographychildrenearly thelarcheobesityoverweightprecocious pubertyultrasonography.

Identifiers

PMID35193333
PMCPMC10226351
OpenAlexW4213441284

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.