ArticleAmerican journal of infection control2022
The impact of COVID-19 vaccination on case fatality rates in a city in Southern Brazil.
Article in American journal of infection control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- COVID-19 Mortality and Temporal Trends in a Mid-Sized Southern Brazilian City (2020-2023): A Population-Based Retrospective Study.Health science reports · 2026Article
- On the dynamics of a COVID-19 model with vaccination and social processes.Scientific reports · 2025Article
- SARS-CoV-2 infection and vaccination in patients with pituitary diseases: the experience of a Brazilian reference center.Pituitary · 2024Observational
- Development and validation of a nomogram for predicting in-hospital survival rates of patients with COVID-19.Heliyon · 2024Article
- COVID-19 transmission dynamics and the impact of vaccination: modelling, analysis and simulations.Royal Society open science · 2023Article
- The Omicron Lineages BA.1 and BA.2 (Viruses · 2023Article
- Dermatological Manifestations in COVID-19: A Case Study of SARS-CoV-2 Infection in a Genetic Thrombophilic Patient with Mthfr Mutation.Pathogens (Basel, Switzerland) · 2023Article
- COVID-19 vaccination and case fatality rates: a case report in a Brazilian municipality.Cadernos de saude publica · 2023Article
- Machine learning and comorbidity network analysis for hospitalized patients with COVID-19 in a city in Southern Brazil.Smart health (Amsterdam, Netherlands) · 2022Article
- Knowledge and Acceptance of the COVID-19 Vaccine for COVID-19 Disease Prevention among the Indian Population: A Mixed-Method Study.Vaccines · 2022Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent studies have established that vaccination plays a significant role in reducing COVID-19-related deaths. Here, we investigated differences in COVID-19 case fatality rates (CFRs) among vaccinated and unvaccinated populations, and analyzed whether the age composition of confirmed cases has a significant effect on the variations in the observed CFRs across these groups.
methodsThe study considered 59,853 confirmed cases and 1,687 deaths from COVID-19, reported between January 1 to October 20, 2021, by the Health Department of Londrina, a city in Southern Brazil. We used Negative Binomial regression models to estimate CFRs according to vaccination status and age range.
resultsThere are significant differences between the CFR for fully vaccinated and unvaccinated populations (IRR = 0.596, 95% CI [0.460 - 0.772], P < .001). Vaccinated populations experience fatality rates 40.4% lower than non-vaccinated. In addition, the age composition of confirmed cases explains more than two-thirds of the variation in the CFR between these 2 groups.
conclusionsOur novel findings reinforce the importance of vaccination as an essential public health measure for reducing COVID-19 fatality rates in all age groups. The results also provide means for accurately assessing differences in CFRs across vaccinated and unvaccinated populations. Such assessment is essential to inform and determine appropriate containment and mitigation interventions in Brazil and elsewhere.
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