Evidence map›Paper›PMID 35192899›Full record

ArticleJournal of the American Academy of Dermatology2022

Association between serum lactate dehydrogenase and cutaneous immune-related adverse events among patients on immune checkpoint inhibitors for advanced melanoma.

Maria S Asdourian, Tracey S Otto, Ted V Jacoby, Nishi Shah, Leah L Thompson, Steven M Blum, Kerry L Reynolds, Yevgeniy R Semenov, Donald P Lawrence, Ryan J Sullivan and 3 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Academy of Dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Maria S AsdourianHarvard Medical School, Boston, Massachusetts; Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts.
Tracey S OttoDepartment of Dermatology, Massachusetts General Hospital, Boston, Massachusetts; Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey.
Ted V JacobyDepartment of Dermatology, Massachusetts General Hospital, Boston, Massachusetts; University of Hawaii at Manoa John A. Burns School of Medicine, Honolulu, Hawaii.
Nishi ShahDepartment of Dermatology, Massachusetts General Hospital, Boston, Massachusetts; Virginia Commonwealth University School of Medicine, Richmond, Virginia.
Leah L ThompsonHarvard Medical School, Boston, Massachusetts; Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts.
Steven M BlumHarvard Medical School, Boston, Massachusetts; Department of Medicine, Division of Hematology and Oncology, Massachusetts General Hospital, Boston, Massachusetts.
Kerry L ReynoldsHarvard Medical School, Boston, Massachusetts; Department of Medicine, Division of Hematology and Oncology, Massachusetts General Hospital, Boston, Massachusetts.
Yevgeniy R SemenovHarvard Medical School, Boston, Massachusetts; Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts.
Donald P LawrenceHarvard Medical School, Boston, Massachusetts; Department of Medicine, Division of Hematology and Oncology, Massachusetts General Hospital, Boston, Massachusetts.
Ryan J SullivanHarvard Medical School, Boston, Massachusetts; Department of Medicine, Division of Hematology and Oncology, Massachusetts General Hospital, Boston, Massachusetts.
Genevieve M BolandHarvard Medical School, Boston, Massachusetts; Department of Surgery, Division of Surgical Oncology, Massachusetts General Hospital, Boston, Massachusetts.
Alexandra-Chloé VillaniHarvard Medical School, Boston, Massachusetts; Department of Medicine, Center for Immunology and Inflammatory Diseases and Center for Cancer Research, Massachusetts General Hospital, Boston, Massachusetts.
Steven T ChenHarvard Medical School, Boston, Massachusetts; Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts. Electronic address: stchen@partners.org.
Massachusetts General Hospital · US

Funding

NCI NIH HHS L30 CA264747
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Immune Checkpoint InhibitorsMelanomaHumansImmunotherapyIpilimumabLactate DehydrogenasesImmune Checkpoint InhibitorsIpilimumabLactate Dehydrogenasescutaneous immune-related adverse eventsdermatologic toxicitiesimmune checkpoint inhibitorimmune-related adverse eventsimmunotherapymelanomaserum LDHtumor burden

Identifiers

PMID35192899
PMCPMC10796160
OpenAlexW4212808519

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.