Evidence map›Paper›PMID 35192798›Full record

ArticleArchives of physical medicine and rehabilitation2022

Predictive Equations Overestimate Resting Metabolic Rate in Survivors of Chronic Stroke.

Alice S Ryan, Maria Novitskaya, Alice L Treuth

Open access · greenAbstract read
In one paragraph

Article in Archives of physical medicine and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Alice S RyanDivision of Gerontology, Geriatrics, and Palliative Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD; Baltimore Veterans Administration Maryland Health Care System Geriatric Research, Education and Clinical Center (GRECC), Baltimore, MD. Electronic address: aryan@som.umaryland.edu.
Maria NovitskayaDivision of Gerontology, Geriatrics, and Palliative Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.
Alice L TreuthDivision of Gerontology, Geriatrics, and Palliative Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.
University of Maryland, Baltimore · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Aging, Inflammation and Exercise in Chronic StrokeR01AG030075 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI HAFER-MACKO, CHARLENE E, RYAN, ALICE S. · 2008 to 2012
$2.4M
Summer Program in Obesity, Diabetes and Nutrition Training (SPORT)T35DK095737 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI STEINLE, NANETTE I · 2012 to 2021
$859k
Resistive Training Combined with Nutritional Therapy after StrokeI01RX001461 · VA · BALTIMORE VA MEDICAL CENTER · PI IVEY, FREDERICK M., RYAN, ALICE S. · 2015 to 2021
–
RR&D Research Career Scientist Award ApplicationIK6RX003977 · VA · BALTIMORE VA MEDICAL CENTER · PI ALICE S. RYAN · 2022 to 2026
–
NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG030075NIDDK NIH HHS T35 DK095737RRD VA I01 RX001461RRD VA IK6 RX003977
6 · The paper itself

Abstract

objectiveTo measure resting metabolic rate (RMR) in survivors of chronic (>3 months prior) stroke (mean ± SEM age, 61±7.5 years) and to compare to predicted RMR using predictive equations in adults without stroke.

designCross-sectional study.

settingHospital.

participantsSurvivors of stroke (N=71).

interventionNot applicable.

main outcome measuresRMR was measured by indirect calorimetry. Participants underwent a total body dual-energy x-ray absorptiometry scan and treadmill test for peak oxygen consumption (V̇o

resultsRMR measured (1552±319 kcal/d) was significantly lower than 9 predicted RMR values (all P<.001), with the best being McArdle-Katch (1652±233 kcal/d), Livingston (1677±230 kcal/d), and Mifflin (1707±242 kcal/d). The Institute of Medicine of the National Academies (2437±386 kcal/d) had the largest discrepancy with measured RMR. Predicted RMR determined with 8 of 9 equations was between 9% and 18% greater than measured RMR. Appendicular lean mass (r=0.64, P<.001), total lean mass (r=0.64, P<.001), and V̇o

conclusionsRMR predictive equations established in adults without stroke are not appropriate for the population with stroke population, indicating the need to measure RMR until a more accurate predictive equation is developed. This could support modifications to nutritional intake guidelines in patients with conditions of muscle atrophy. If measurement of RMR is not feasible, the Katch-McArdle equation should be used to estimate RMR in a patient with stroke because on average it provides the lowest percentage overestimate compared with other equations.

Indexed as

Basal MetabolismStrokeAdultAgedBody CompositionBody Mass IndexBrain Damage, ChronicCalorimetry, IndirectCross-Sectional StudiesEnergy MetabolismHumansMiddle AgedSurvivorsAgingEnergy metabolismMusclesRehabilitationStroke

Identifiers

PMID35192798
PMCPMC9246861
OpenAlexW4212838332

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.