ArticlePLoS neglected tropical diseases2022
First laboratory confirmation and sequencing of Zaire ebolavirus in Uganda following two independent introductions of cases from the 10th Ebola Outbreak in the Democratic Republic of the Congo, June 2019.
Article in PLoS neglected tropical diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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17 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- The Impact of Diagnostic Delays and Timeliness of Response on Ebola Disease outbreak-level case-fatality Ratios in Uganda (2000-2023): a Rapid Systematic Review and meta-analysis.Journal of epidemiology and global health · 2025Pooled it
- Local implementation of scalable malaria molecular surveillance in a low-resource setting: a North-South collaborative model.Malaria journal · 2026Article
- Donor dependency and pandemic readiness: insights from the 2026 Ebola Bundibugyo outbreak in the East African community.Frontiers in public health · 2026Article
- High-Resolution Mapping of Environmental Suitability for Reported Ebola Spillover Events in Uganda to Inform Surveillance and Preparedness.Journal of tropical medicine · 2026Article
- Utility of TaqMan Array Cards for detection of acute febrile illness etiologies in patients suspected of viral hemorrhagic fever infections.BMC infectious diseases · 2025Article
- Strategies Utilized During Sudan Virus Disease Outbreak Response in Kampala City, Uganda, 2022 - 2023.Journal of epidemiology and global health · 2025Article
- Rapid laboratory confirmation of the 2025 Sudan Virus Disease (Svd) index case in Uganda.BMC infectious diseases · 2025Article
- Identification of Anthrax as the Cause of a Cluster of Unexplained Deaths, Uganda, 2023: The Role of Metagenomic Next-Generation Sequencing and Postmortem Specimens.The American journal of tropical medicine and hygiene · 2025Article
- A novel post-mortem pathogen discovery program detects an outbreak of Echovirus E7: Uganda, 2022-2023.Frontiers in microbiology · 2025Article
- Scoping review of countries' practices missed by health emergency preparedness and response quantitative tools: COVID-19 and Ebola response experiences.BMJ public health · 2024Article
- Ebola disease outbreak caused by the Sudan virus in Uganda, 2022: a descriptive epidemiological study.The Lancet. Global health · 2024Article
- Pathogen genomic surveillance status among lower resource settings in Asia.Nature microbiology · 2024Article
- Article
- Viruses of free-roaming and hunting dogs in Uganda show elevated prevalence, richness and abundance across a gradient of contact with wildlife.The Journal of general virology · 2024Article
- Recent Advances in Crimean-Congo Hemorrhagic Fever Virus Detection, Treatment, and Vaccination: Overview of Current Status and Challenges.Biological procedures online · 2024Review
- Viruses associated with measles-like illnesses in Uganda.The Journal of infection · 2024Article
- Detection of Sporadic Outbreaks of Rift Valley Fever in Uganda through the National Viral Hemorrhagic Fever Surveillance System, 2017-2020.The American journal of tropical medicine and hygiene · 2023Article
Corrections and comments
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Authors and funding
16 authors at 4 institutions in 2 countries.
Funding
Abstract
Uganda established a domestic Viral Hemorrhagic Fever (VHF) testing capacity in 2010 in response to the increasing occurrence of filovirus outbreaks. In July 2018, the neighboring Democratic Republic of Congo (DRC) experienced its 10th Ebola Virus Disease (EVD) outbreak and for the duration of the outbreak, the Ugandan Ministry of Health (MOH) initiated a national EVD preparedness stance. Almost one year later, on 10th June 2019, three family members who had contracted EVD in the DRC crossed into Uganda to seek medical treatment. Samples were collected from all the suspected cases using internationally established biosafety protocols and submitted for VHF diagnostic testing at Uganda Virus Research Institute. All samples were initially tested by RT-PCR for ebolaviruses, marburgviruses, Rift Valley fever (RVF) virus and Crimean-Congo hemorrhagic fever (CCHF) virus. Four people were identified as being positive for Zaire ebolavirus, marking the first report of Zaire ebolavirus in Uganda. In-country Next Generation Sequencing (NGS) and phylogenetic analysis was performed for the first time in Uganda, confirming the outbreak as imported from DRC at two different time point from different clades. This rapid response by the MoH, UVRI and partners led to the control of the outbreak and prevention of secondary virus transmission.
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Registered trials
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