Evidence map›Paper›PMID 35192149›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2022

The health-related quality of life in hyperhidrosis and co-morbidities.

Mattias A S Henning, Kristina S Ibler, Isabella Loft, Sisse R Ostrowski, Christian Erikstrup, Kaspar R Nielsen, Mie T Bruun, Henrik Ullum, Maria Didriksen, Khoa M Dinh and 2 more

Abstract read
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In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Quality of life in individuals with primary hyperhidrosis: a systematic review and meta-analysis.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023
    Pooled it
  2. Review
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  7. Review
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  9. The temporal association of hyperhidrosis and its comorbidities - a nationwide hospital-based cohort study.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Mattias A S HenningDepartment of Dermatology, Zealand University Hospital, Roskilde, Denmark. maahe@regionsjaelland.dk.ORCID http://orcid.org/0000-0003-1991-2248
Kristina S IblerDepartment of Dermatology, Zealand University Hospital, Roskilde, Denmark.
Isabella LoftDepartment of Clinical Immunology, Zealand University Hospital, Næstved, Denmark.
Sisse R OstrowskiDepartment of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
Christian ErikstrupDepartment of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
Kaspar R NielsenDepartment of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark.
Mie T BruunDepartment of Clinical Immunology, Odense University Hospital, Odense, Denmark.
Henrik UllumStatens Serum Institute, Copenhagen, Denmark.
Maria DidriksenDepartment of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
Khoa M DinhDepartment of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
Ole B Pedersen *Department of Clinical Immunology, Zealand University Hospital, Næstved, Denmark.
Gregor B E Jemec *Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.
Zealand University Hospital · DKAarhus University Hospital · DKCopenhagen University Hospital · DKAalborg University Hospital · DKOdense University Hospital · DKStatens Serum Institut · DK

Funding

Danish rheumatism association R194-A6956LEO Fondet LF-18002
6 · The paper itself

Abstract

purposeHyperhidrosis has been associated with a reduced health-related quality of life (HRQoL). The role of common confounding factors of this association such as stress and socioeconomic status, however, remain largely unexplored, and may affect the management strategy for hyperhidrosis. Therefore, the study objective was to compare the HRQoL in individuals with and without hyperhidrosis while adjusting for confounders.

methodsIn this retrospective cohort study, data on the HRQoL measured by the short-form-12 questionnaire and self-reported hyperhidrosis were collected from the Danish Blood Donor Study-cohort. Data on international classification of disease-10 codes and redeemed prescriptions were collected from nationwide registries. Linear regression investigated the association between hyperhidrosis and HRQoL.

resultsTotal 2794 (9.1%) of 30,808 blood donors had self-reported hyperhidrosis and 284 (0.2%) of 122,225 had hospital diagnosed hyperhidrosis. Self-reported hyperhidrosis was associated with a reduced mental HRQoL (adjusted beta coefficient - 1.10; 95% confidence interval - 1.37, - 0.82; p < 0.001) and physical HRQoL (adjusted beta coefficient - 0.90; 95% confidence interval - 1.09, - 0.70; p < 0.001). Hospital diagnosed hyperhidrosis was associated with a reduced mental HRQoL (adjusted beta coefficient - 0.91; 95% confidence interval - 1.82, - 0.04; p = 0.049).

conclusionHyperhidrosis is associated with a reduced HRQoL, independently of confounders or mode of diagnosis. This supports an approach primarily targeting hyperhidrosis.

Indexed as

HyperhidrosisQuality of LifeHumansMorbidityRetrospective StudiesSurveys and QuestionnairesHealth-related quality of lifeHyperhidrosisMental component summaryPhysical component summary

Identifiers

PMID35192149
OpenAlexW4212945310

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.