ReviewJournal of ophthalmic inflammation and infection2022
Acute syphilitic posterior placoid chorioretinitis: when the great mimicker cannot pretend any more; new insight of an old acquaintance.
Review in Journal of ophthalmic inflammation and infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 28 citations in OpenAlex.
- Questions Ophthalmology Trainees Ask About Ocular Syphilis: A Question-Driven Narrative Review.Cureus · 2026Review
- Advanced Multimodal Imaging in Granulomatous Uveitis: From Differential Diagnosis to Treatment Monitoring and Surgical Integration.Journal of clinical medicine · 2026Review
- Multiple evanescent white dot syndrome and presentations similar to multiple evanescent white dot syndrome in other disorders: a narrative review.International journal of ophthalmology · 2025Review
- Atypical Acute Ischemic Choriocapillaritis: A Case Report.Clinical case reports · 2024Article
- A case of acute syphilitic posterior placoid chorioretinitis showing improved choroidal blood flow after treatment.American journal of ophthalmology case reports · 2023Article
- Fundus autofluorescence in uveitis: from pathogenesis to imaging interpretation.International ophthalmology · 2023Review
- Article
- Posterior placoid-like maculopathy and macular hole associated with vitamin A deficiency.American journal of ophthalmology case reports · 2023Article
- Secondary Syphilis Presenting as Bilateral Simultaneous Papillitis in an Immunocompetent Individual.Cureus · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo review the multimodal imaging patterns of Acute Syphilitic Posterior Placoid Chorioretinitis (ASPPC).
methodsA systematic review.
resultsSyphilis has started to attract the attention of researchers once again due to recent surges, with The World Health Organization (WHO) reporting around 12 million new cases per year. When left untreated, syphilis has a mortality rate of 8-58%, with a higher death rate in males. Eye manifestations occur both in secondary and tertiary stages of syphilis, although ocular involvement may occur at any stage of the disease. Syphilis has been always recognized as "the great mimicker" since it can have multiple clinical patterns of presentation. However, Acute Syphilitic Posterior Placoid Chorioretinitis (ASPPC) represents the typical pattern of the disease and can be easily distinguished. In addition, the advent of modern technologies and the progress made in multimodal imaging have provided more details on its identikit: the pattern of pre-retinal, retinal, retinochoroidal and optic nerve involvement can be identified before going through the laboratory work-up for a correct and appropriate investigation of the disease.
conclusionThis review highlights the peculiar pattern of ASPPC, by reporting the diagnostic process made by all the imaging techniques used for a correct multimodal imaging assessment.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.