Evidence map›Paper›PMID 35192046›Full record

ArticleArchives of microbiology2022

Detection of capsular genotypes of methicillin-resistant Staphylococcus aureus and clonal distribution of the cap5 and cap8 genes in clinical isolates.

Gabriela Echániz-Aviles, Maria Elena Velazquez-Meza, Brian Rodríguez-Arvizu, Maria Noemi Carnalla-Barajas, Araceli Soto Noguerón

Open access · bronzeAbstract read
In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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  4. Antimicrobial resistance ofVeterinary world · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gabriela Echániz-AvilesCentro de Investigación sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Universidad 655, Cerrada de los Pinos y Caminera, Col. Sta. María Ahuacatitlán, CP 62100, Cuernavaca, Morelos, Mexico.
Maria Elena Velazquez-MezaCentro de Investigación sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Universidad 655, Cerrada de los Pinos y Caminera, Col. Sta. María Ahuacatitlán, CP 62100, Cuernavaca, Morelos, Mexico. mevelaz@insp.mx.ORCID http://orcid.org/0000-0003-0829-9740
Brian Rodríguez-ArvizuCentro de Investigación sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Universidad 655, Cerrada de los Pinos y Caminera, Col. Sta. María Ahuacatitlán, CP 62100, Cuernavaca, Morelos, Mexico.
Maria Noemi Carnalla-BarajasCentro de Investigación sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Universidad 655, Cerrada de los Pinos y Caminera, Col. Sta. María Ahuacatitlán, CP 62100, Cuernavaca, Morelos, Mexico.
Araceli Soto NoguerónCentro de Investigación sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Universidad 655, Cerrada de los Pinos y Caminera, Col. Sta. María Ahuacatitlán, CP 62100, Cuernavaca, Morelos, Mexico.
Instituto Nacional de Salud Pública · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Up until now, the capsular polysaccharides of Staphylococcus aureus have been classified into 11 types, of which only 2 types 5 and 8; (encoded by the genes cap5 and cap8, respectively) are present in 80-90% of clinically significant strains. The aim of the present study was to detect the capsular genotypes of methicillin-resistant S. aureus (MRSA) clinical isolates and determined their clonal distribution. A total of 262 MRSA clinical isolates from different hospitals in Mexico were analyzed by PCR to determine the genetic characteristics of their capsule expression. Pulsed-field gel electrophoresis and multilocus sequence typing were used to characterize the isolates. The analysis of the capsular genotypes among MRSA isolates showed that 245 isolates (93.5%) contained the cap5 gene, and that the remaining 17 (6.5%) encoded the cap8 gene. The MRSA isolates were grouped into four clonal groups. The identification of the capsular genotypes of clinical isolates of MRSA is important information because potential vaccine formulations against S. aureus involve capsular polysaccharides.

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsElectrophoresis, Gel, Pulsed-FieldGenotypeHumansMicrobial Sensitivity TestsMultilocus Sequence TypingStaphylococcus aureusCapsular genotypesClinical isolatescp5cp8MRSA

Identifiers

PMID35192046
PMCPMC8861481
OpenAlexW4212806039

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.