Evidence map›Paper›PMID 35191951›Full record

ArticleThe Journal of cell biology2022

Closing the gap: Tricellulin/α-catenin interaction maintains epithelial integrity at vertices.

Lotte van den Goor, Ann L Miller

Open access · greenAbstract readEditorialComment
In one paragraph

Article in The Journal of cell biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Lotte van den GoorDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI.ORCID 0000-0002-8541-2949
Ann L MillerDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI.ORCID 0000-0002-7293-764X
University of Michigan · US

Funding

Regulation of localized RhoA activity in dividing epithelial cellsR01GM112794 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MILLER, ANN LOUISE · 2015 to 2023
$3.0M
American Heart Association-American Stroke Association 906189NIGMS NIH HHS R01 GM112794NIH HHS 2R01 GM112794
6 · The paper itself

Abstract

Tricellular junctions play a critical role in regulating epithelial barrier function. In this issue, Cho et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202009037) demonstrate a novel interaction between tricellulin and α-catenin, which connects tricellular junctions to the actomyosin cytoskeleton, thus supporting the epithelial barrier at cell vertices.

Indexed as

MARVEL Domain Containing 2 ProteinTight JunctionsActin CytoskeletonActomyosinalpha CateninActomyosinalpha CateninMARVEL Domain Containing 2 Protein

Identifiers

PMID35191951
PMCPMC8932530
OpenAlexW4213330054

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.