Evidence map›Paper›PMID 35191898›Full record

Trial reportOncology nursing forum2022

An Exploratory Study of Cognitive Function and Central Adiposity in Men Receiving Androgen Deprivation Therapy for Prostate Cancer.

Jamie S Myers, Alana Manson, Sandra A Billinger, William Parker, Jill Hamilton-Reeves, Francisco J Diaz, Ron Krebill, Sally Maliski

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Oncology nursing forum, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Risks associated with cognitive function and management strategies in the clinical use of ADT: a systematic review from clinical and preclinical studies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jamie S MyersUniversity of Kansas.
Alana MansonUniversity of Kansas.
Sandra A BillingerUniversity of Kansas Medical Center.
William ParkerUniversity of Kansas Health System.
Jill Hamilton-ReevesUniversity of Kansas Medical Center.
Francisco J DiazUniversity of Kansas Medical Center.
Ron KrebillUniversity of Kansas Medical Center.
Sally MaliskiUniversity of Kansas.
University of Kansas · US

Funding

Transgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ROY A. JENSEN · 2012 to 2026
$40.1M
Staying Strong and Healthy for Androgen Deprivation Therapy for Latino MenR01NR014518 · NINR · UNIVERSITY OF KANSAS MEDICAL CENTER · PI MALISKI, SALLY L · 2014 to 2019
$2.5M
NCI NIH HHS P30 CA168524NINR NIH HHS R01 NR014518
6 · The paper itself

Abstract

objectivesTo prospectively assess cognitive function, anthropomorphic measures, and bone mineral density in men receiving androgen deprivation therapy (ADT) for prostate cancer; explore relationships between cognitive function and central adiposity; and gather preliminary data from a personalized education, exercise, and nutrition intervention. SAMPLE &

setting33 participants consented from a randomized controlled intervention trial. METHODS & VARIABLES: Neurocognitive performance and self-report of cognitive function were assessed at baseline and 6 and 12 months. Dual-energy x-ray absorptiometry (DEXA) scans were obtained at baseline and 6 months.

resultsNo between-group differences in cognitive function were demonstrated. Increased visceral adiposity was not associated with decrements in visuospatial abilities. Significant increases in fat mass without increases in body mass index or waist-hip ratio provided further evidence for DEXA as the preferred central adiposity measure. IMPLICATIONS FOR NURSING: Well-powered prospective research is needed to fully characterize the effects of ADT on cognitive function and the potential benefits of exercise and nutrition-based interventions.

Indexed as

Androgen AntagonistsProstatic NeoplasmsAdiposityAndrogensBone DensityCognitionHumansMaleProspective StudiesAndrogen AntagonistsAndrogensandrogen deprivationcentral adipositycognitive functionprostate cancer

Identifiers

PMID35191898
PMCPMC12878646
OpenAlexW4213318797

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.