ArticleTopics in antiviral medicine
Neurocognition and the Aging Brain in People With HIV: Implications for Screening.
Article in Topics in antiviral medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 13 citations in OpenAlex.
- Evidence that intrinsic brain connectivity moderates the association between gait and neurocognitive function in people living with HIV.Journal of neurovirology · 2026Article
- Cytomegalovirus Immune Responses and Cognitive Impairment in People With Human Immunodeficiency Virus.The Journal of infectious diseases · 2026Article
- Examining Age as Moderating Associations Between Methamphetamine Abstinence and Cognitive Function in People with HIV.Viruses · 2026Article
- Exploring the potential of cognitive intra-individual variability in HIV care and research in adults with HIV: a concept analysis.Applied neuropsychology. Adult · 2026Review
- Neuroimmune Correlates of HIV and Marijuana Use: Peripheral Biomarkers and Cognitive Function.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2026Article
- Smoldering in the sanctuary: HIV-associated brain injury in the ART era.The Journal of clinical investigation · 2026Review
- Interferon-induced protein IFIT3 as a molecular nexus of neuroinflammation in Alzheimer's disease and HIV-associated neurocognitive disorders.Journal of neuroinflammation · 2026Article
- HIV infection in microglia leads to senescence, triggering activation of neurotoxicity pathways.bioRxiv : the preprint server for biology · 2025Article
- Viruses and the Brain-A Relationship Prone to Trouble.Viruses · 2025Review
- Executive Functioning Training for Reducing Cognitive Intra-Individual Variability in People Living with HIV: A Pilot Randomized, Controlled Trial Protocol.Nursing (Auckland, N.Z.) · 2025Article
- Expert Consensus Statement on an Updated Definition of Unintended Weight Loss Among Persons With Human Immunodeficiency Virus in the Modern Treatment Era.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Review
- Article
- Exercise to Prevent Accelerated Vascular Aging in People Living With HIV.Circulation research · 2024Review
- Non-pharmaceutical interventions for people living with HIV with cognitive impairment: A scoping review.PloS one · 2024Article
- Cellular rejuvenation to combat HIV-1-related neurocognitive impairment.Trends in microbiology · 2024Article
- Cognitive impairment in people living with HIV: consensus recommendations for a new approach.Nature reviews. Neurology · 2023Review
- Undiagnosed Cognitive Impairment and Impact on Instrumental Activities of Daily Living Among People With HIV Infection in Primary Care.Open forum infectious diseases · 2023Article
- Low incidence of advanced neurological burden but high incidence of age-related conditions that are dementia risk factors in aging people living with HIV: a data-linkage 10-year follow-up study.Journal of neurovirology · 2023Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
The introduction of effective antiretroviral therapy (ART) has converted HIV infection from a lethal disease to a manageable chronic condition for most people. The drastic improvement in life expectancy of people with HIV has led to an expansion of the aging population of people with HIV globally. Recent research indicates that people with HIV on suppressive ART still sustain persistent, albeit alleviated, systemic and cerebral immune activation that can facilitate age-related causes of cognitive impairment (CI), including neurodegenerative and cerebrovascular diseases. Although HIV-associated neurocognitive disorder remains prevalent in older people with HIV on suppressive ART, the co-occurrence of other age-related causes of CI makes the investigation and management of CI more challenging. More importantly, it remains unknown if the neuropsychiatric manifestations of HIV-associated neurocognitive disorder are modified by the presence of age-related causes of CI, such as Alzheimer disease, and vice versa. This article will review findings regarding the interaction between HIV-1 infection and age-related comorbidities, namely atherosclerosis and neurodegenerative diseases, followed by cognitive outcomes of people with HIV in longitudinal studies. Cognitive symptoms of people with HIV on stable ART will be discussed. The review will go through the latest recommendations for cognitive screening in different HIV management guidelines, as well as the usefulness of various screening tools in the setting of stable viral suppression.
Indexed as
Identifiers
35191658PMC8862751W4213402082What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.