Evidence map›Paper›PMID 35191563›Full record

ReviewThe Journal of eukaryotic microbiology2022

New insights into the role of acidocalcisomes in trypanosomatids.

Roberto Docampo, Guozhong Huang

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of eukaryotic microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. A spatially resolved elemental nanodomain organization within acidocalcisomes inProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  8. Review
  9. The endoplasmic reticulum of trypanosomatids: An unrevealed road for chemotherapy.Frontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Roberto DocampoCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia, USA.ORCID 0000-0003-4229-8784
Guozhong HuangCenter for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia, USA.
University of Georgia · US

Funding

Piezo channels and calcium signaling in Trypanosoma cruziR21AI156096 · NIAID · UNIVERSITY OF GEORGIA · PI DOCAMPO, ROBERTO · 2021 to 2022
$415k
National Institute of Allergy and Infectious Diseases AI156096NIAID NIH HHS R21 AI156096
6 · The paper itself

Abstract

Acidocalcisomes are electron-dense organelles rich in polyphosphate and inorganic and organic cations that are acidified by proton pumps, and possess several channels, pumps, and transporters. They are present in bacteria and eukaryotes and have been studied in greater detail in trypanosomatids. Biogenesis studies of trypanosomatid acidocalcisomes found that they share properties with lysosome-related organelles of animal cells. In addition to their described roles in autophagy, cation and phosphorus storage, osmoregulation, pH homeostasis, and pathogenesis, recent studies have defined the role of these organelles in phosphate utilization, calcium ion (Ca

Indexed as

CalciumOrganellesAnimalsEukaryotaPhosphorusPolyphosphatesCalciumPhosphorusPolyphosphatesacidocalcisomecalciumchannelsexchangersphosphatepolyphosphatepumpstrypanosoma

Identifiers

PMID35191563
PMCPMC10350294
OpenAlexW4212851483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.