Evidence map›Paper›PMID 35191202›Full record

Trial reportJournal of diabetes investigation2022

β-Cell function and body mass index are predictors of exercise response in elderly patients with prediabetes.

Yali He, Yanhong Feng, Junli Shi, Hong Tang, Linhui Chen, Qingqing Lou

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of diabetes investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Exercise therapy for sarcopenia and diabetes.World journal of diabetes · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yali HeTaiyuan Diabetes Hospital, Taiyuan, China.
Yanhong FengTaiyuan Diabetes Hospital, Taiyuan, China.
Junli ShiTaiyuan Diabetes Hospital, Taiyuan, China.
Hong TangChengdu Ruien Diabetes Hospital, Chendu, China.
Linhui ChenTaiyuan Diabetes Hospital, Taiyuan, China.
Qingqing LouThe First Affiliated Hospital of Hainan Medical University, Haikou, China.ORCID https://orcid.org/0000-0002-4743-0900
Taiyuan Central Hospital · CNBeijing Shijingshan Hospital · CNTen Chen Hospital · TW

Funding

National Natural Science Foundation of China 81370923State Administration of Traditional Chinese Medicine of the People's Republic of China JDZX2015132
6 · The paper itself

Abstract

AIMS/

introductionTo explore the predicting factors of exercise response (whether the participants converted to diabetes) in elderly patients with prediabetes. MATERIALS AND

methodsThis is a retrospective subgroup analysis of the registered clinical trial with previous publication of the same cohort. A total of 248 participants with prediabetes were randomized to the aerobic training (n = 83) group, resistance training (n = 82) group and control group (n = 83). The patients who finished the 2-year exercise intervention were included in this analysis to explore the factors impacting exercise response.

resultsA total of 113 patients with prediabetes completed 2 years of exercise, with 56 participants in the aerobic exercise group and 57 in the resistance exercise group. Patients who reversed to normal glucose tolerance, remained in prediabetes and developed diabetes were 18 (15.90%), 70 (62.00%) and 25 (22.10%), respectively. Logistic regression showed that baseline, homeostatic model 2 assessment of β-cell function (β = -0.143, P = 0.039), hemoglobin A1c (β = 3.301, P = 0.007) and body mass index (β = 0.402, P = 0.012) were related to exercise response, whereas the waist-to-hip ratio (β = -3.277, P = 0.693) and types of exercise (β = 1.192, P = 0.093) were not significantly related to exercise response.

conclusionsBaseline homeostatic model 2 assessment of β-cell function, hemoglobin A1c and body mass index were the predictors for the response to exercise in elderly patients with prediabetes.

Indexed as

Prediabetic StateAgedBlood GlucoseBody Mass IndexExerciseGlycated HemoglobinHumansRetrospective StudiesBlood GlucoseGlycated HemoglobinElderly patientsExercise responsePrediabetes

Identifiers

PMID35191202
PMCPMC9248431
OpenAlexW4212780338

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.