ArticleThe international journal of cardiovascular imaging2022
Right atrial and ventricular strain detects subclinical changes in right ventricular function in precapillary pulmonary hypertension.
Article in The international journal of cardiovascular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic Value of Cardiac Magnetic Resonance in Assessing Right Ventricular Strain in Cardiovascular Disease: A Systematic Review and Meta-Analysis.Reviews in cardiovascular medicine · 2022Pooled it
- Sequential Changes in Right Ventricular Strain During the Development of Pulmonary Hypertension Assessed With Magnetic Resonance Feature Tracking: An Animal Study.Korean journal of radiology · 2026Article
- Prevalence and Clinical Importance of Right Ventricular Involvement in Mild Dilated Cardiomyopathy.Journal of the American Heart Association · 2026Article
- Echocardiographic Deformation Imaging of the Right Atrium: A New Paradigm in Noninvasive Hemodynamic Assessment.Current cardiology reports · 2026Review
- Cardiac MRI-derived ventricular-pulmonary arterial coupling predicts outcomes in connective tissue disease-associated pulmonary arterial hypertension patients.European journal of radiology open · 2025Article
- Echocardiographic Evaluation of Pulmonary Hypertension: A Contemporary Review of the American Society of Echocardiography (ASE) Guidelines and Emerging Modalities.Current cardiology reports · 2025Review
- Methamphetamine-Associated Pulmonary Arterial Hypertension Is Associated With Worse Right Ventricular Function Than Idiopathic Pulmonary Arterial Hypertension: A Matched Study.Echocardiography (Mount Kisco, N.Y.) · 2025Article
- Clinical utility of right atrial strain to estimate pulmonary hypertension in comparison with right ventricular free wall longitudinal strain.Fujita medical journal · 2025Article
- A Non-Invasive Approach to Pulmonary Hypertension.Journal of clinical medicine · 2025Review
- Cardiac Functional Assessment by Magnetic Resonance Imaging.Cardiology discovery · 2024Review
- Cardiac Magnetic Resonance Imaging in the Evaluation of Functional Impairments in the Right Heart.Diagnostics (Basel, Switzerland) · 2024Review
- CMR to characterize myocardial structure and function in heart failure with preserved left ventricular ejection fraction.European heart journal. Cardiovascular Imaging · 2024Review
- Value of cardiac magnetic resonance feature-tracking in Arrhythmogenic Cardiomyopathy (ACM): A systematic review and meta-analysis.International journal of cardiology. Heart & vasculature · 2024Review
- The Added Value of Advanced Echocardiography for the Morpho-Functional and Prognostic Evaluation of the Right Heart in Dilated Cardiomyopathy: Do Not Forget about the Right Atrium.Journal of clinical medicine · 2024Article
- The Prognostic Value of One-Year Changes in Biventricular Mechanics for Three-Year Survival in Patients with Precapillary Pulmonary Hypertension: A Cardiovascular Magnetic Resonance Feature Tracking Study.Medicina (Kaunas, Lithuania) · 2024Article
- Characteristics and prognostic value of cardiac magnetic resonance strain analysis in patients with different phenotypes of heart failure.Frontiers in cardiovascular medicine · 2024Article
- The impact of image and performance enhancing drugs on atrial structure and function in resistance trained individuals.Echo research and practice · 2023Article
- Phenotyping heart failure by cardiac magnetic resonance imaging of cardiac macro- and microscopic structure: state of the art review.European heart journal. Cardiovascular Imaging · 2023Review
- Different phenotype of left atrial function impairment in patients with hypertrophic cardiomyopathy and hypertension: comparison of healthy controls.Frontiers in cardiovascular medicine · 2023Article
- Editor's choice to the Aug 2022 issue : Right atrial and right ventricular strain in patients with precapillary pulmonary hypertension, and advanced ultrasound techniques in arterial diseases.The international journal of cardiovascular imaging · 2022Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Right ventricular (RV) ejection fraction (EF) by cardiac magnetic resonance (CMR) correlates to outcome in precapillary pulmonary hypertension (pPH) patients, but is insensitive to early changes. Strain might provide incremental information. In this study, we compare right atrial (RA) and RV strain in pPH patients to healthy controls, and evaluate the prognostic value of strain in pPH. In this cross-sectional study, 45 pPH patients and 20 healthy controls underwent CMR, and feature-tracking derived RA and RV strain were evaluated. pPH patients had impaired RA reservoir and conduit strain, and RV longitudinal strain (LS), compared to healthy controls. In pPH patients with preserved RVEF (≥ 50%, n = 18), RA reservoir (35% ± 9 vs. 41% ± 6, p = 0.02) and conduit strain (16% ± 8 vs. 23% ± 5, p = 0.004), and RV-LS (-25% ± 4 vs. -31% ± 4, p < 0.001) remained impaired, compared to healthy controls. The association of strain with the primary endpoint (combination of all-cause death, lung transplantation, and heart failure hospitalization) was evaluated using a multivariable Cox regression model. RV-LS (HR 1.18, 95%-CI 1.04-1.34, p = 0.01) and RA strain (reservoir: HR 0.87, 95%-CI 0.80-0.94, p = 0.001; conduit: HR 0.85, 95%-CI 0.75-0.97, p = 0.02, booster: HR 0.81, 95%-CI 0.71-0.92, p = 0.001) were independent predictors of outcome, beyond clinical and imaging features. In conclusion, pPH patients have impaired RA strain and RV-LS, even when RVEF is preserved. In addition, RA strain and RV-LS were independent predictors of adverse prognosis. These results emphasize the incremental value of RA and RV strain analyses, to detect alterations in RV function, even before RVEF declines.
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