Evidence map›Paper›PMID 35190936›Full record

ArticleClinical and experimental medicine2023

A single dose of COVID-19 vaccine induces a strong T cell and B cell response in healthcare professionals recovered from SARS-CoV-2 infection.

Paula Laranjeira, Tiago Rodrigues, Ana Silva, Pedro Barbosa, Teresa Reis, Cristiana Lopes, Aryane Pinho, Sandra Silva, Isabel Silva, Anabela Carvalho and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and experimental medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Paula LaranjeiraFlow Cytometry Unit (UGOC), Department of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Av. Bissaya Barreto, Bloco de Celas, 3000-075, Coimbra, Portugal.ORCID http://orcid.org/0000-0002-1136-6118
Tiago RodriguesServiço de Saúde Ocupacional, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.ORCID http://orcid.org/0000-0003-1127-0666
Ana SilvaFlow Cytometry Unit (UGOC), Department of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Av. Bissaya Barreto, Bloco de Celas, 3000-075, Coimbra, Portugal.ORCID http://orcid.org/0000-0002-8506-9220
Pedro BarbosaCenter for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.ORCID http://orcid.org/0000-0002-0048-2615
Teresa ReisDepartment of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.ORCID http://orcid.org/0000-0003-3128-7457
Cristiana LopesDepartment of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.
Aryane PinhoCenter for Neuroscience and Cell Biology (CNC), University of Coimbra, Coimbra, Portugal.ORCID http://orcid.org/0000-0003-2235-2237
Sandra SilvaFlow Cytometry Unit (UGOC), Department of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Av. Bissaya Barreto, Bloco de Celas, 3000-075, Coimbra, Portugal.
Isabel SilvaFlow Cytometry Unit (UGOC), Department of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Av. Bissaya Barreto, Bloco de Celas, 3000-075, Coimbra, Portugal.
Anabela CarvalhoFlow Cytometry Unit (UGOC), Department of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Av. Bissaya Barreto, Bloco de Celas, 3000-075, Coimbra, Portugal.
Vânia PachecoServiço de Saúde Ocupacional, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.ORCID http://orcid.org/0000-0002-4011-1173
Fernando RodriguesDepartment of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.
Lucília AraújoDepartment of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.
Isabel AntunesServiço de Saúde Ocupacional, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.
Artur PaivaFlow Cytometry Unit (UGOC), Department of Clinical Pathology, Centro Hospitalar e Universitário de Coimbra (CHUC), Av. Bissaya Barreto, Bloco de Celas, 3000-075, Coimbra, Portugal. artur.paiva@chuc.min-saude.pt.ORCID http://orcid.org/0000-0002-6562-5859
Hospitais da Universidade de Coimbra · PTUniversity of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A broad understanding on how SARS-CoV-2 infection and vaccination mobilize the immune system is necessary to find the best predictors of long-term protection and identify individuals that would benefit from additional vaccine doses. This study aims to understand the effect of a single dose of Pfizer-BioNTech BNT162b2 COVID-19 vaccine, in individuals recovered from SARS-CoV-2 infection, on circulating CD4

Indexed as

COVID-19COVID-19 VaccinesAntibodies, ViralBNT162 VaccineDelivery of Health CareHumansImmunoglobulin AImmunoglobulin GSARS-CoV-2VaccinationAntibodies, ViralBNT162 VaccineCOVID-19 VaccinesImmunoglobulin AImmunoglobulin GCOVID-19SARS-CoV-2Spike-specific IgGSpike-specific T cellsT follicular cellsVaccination

Identifiers

PMID35190936
PMCPMC8860269
OpenAlexW4212868775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.