Evidence map›Paper›PMID 35190732›Full record

ArticleBioinorganic chemistry and applications2022

Enhanced Bioactivity of Pomegranate Peel Extract following Controlled Release from CaCO

Francesca Baldassarre, Viviana Vergaro, Federica De Castro, Francesca Biondo, Gian Paolo Suranna, Paride Papadia, Francesco P Fanizzi, Domenico Rongai, Giuseppe Ciccarella

Abstract read
In one paragraph

Article in Bioinorganic chemistry and applications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Investigating Roasted Açaí (Foods (Basel, Switzerland) · 2025
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesca BaldassarreDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID https://orcid.org/0000-0002-3328-7701
Viviana VergaroInstitute of Nanotechnology, CNR NANOTEC, Consiglio Nazionale Delle Ricerche, Via Monteroni, 73100 Lecce, Italy.ORCID https://orcid.org/0000-0003-3706-6276
Federica De CastroDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID https://orcid.org/0000-0001-5060-293X
Francesca BiondoDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID https://orcid.org/0000-0002-8031-6659
Gian Paolo SurannaInstitute of Nanotechnology, CNR NANOTEC, Consiglio Nazionale Delle Ricerche, Via Monteroni, 73100 Lecce, Italy.ORCID https://orcid.org/0000-0003-2953-0809
Paride PapadiaDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID https://orcid.org/0000-0001-9611-3824
Francesco P FanizziDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID https://orcid.org/0000-0003-3073-5772
Domenico RongaiCREA-IT PE-Research Centre for Engineering and Agro-Food Processing, Via Lombardia, Pescara, Italy.ORCID https://orcid.org/0000-0001-5432-3591
Giuseppe CiccarellaDepartment of Biological and Environmental Sciences, UdR INSTM of Lecce University of Salento, Via Monteroni, 73100 Lecce, Italy.ORCID https://orcid.org/0000-0003-4467-0922

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pomegranate peel extract is rich of interesting bioactive chemicals, principally phenolic compounds, which have shown antimicrobial, anticancer, and antioxidative properties. The aim of this work was to improve extract' bioactivity through the adsorption on calcium carbonate nanocrystals. Nanocrystals revealed as efficient tools for extract adsorption reaching 50% of loading efficiency. Controlled release of the contained metabolites under acidic pH has been found, as it was confirmed by quantitative assay and qualitative study through NMR analysis. Specific functionality of inorganic nanocarriers could be also tuned by biopolymeric coating. The resulting coated nanoformulations showed a great antimicrobial activity against

Identifiers

PMID35190732
PMCPMC8858070

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.