Evidence map›Paper›PMID 35190711›Full record

ReviewNature human behaviour2022

The ConTraSt database for analysing and comparing empirical studies of consciousness theories.

Itay Yaron, Lucia Melloni, Michael Pitts, Liad Mudrik

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature human behaviour, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Review
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  10. On the role of theories in consciousness science.Communications psychology · 2025
    Article
  11. The evolutionary functions of consciousness.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  12. Frontal Disorders and Consciousness: A Review.Current neurology and neuroscience reports · 2025
    Review
  13. Article
  14. Article
  15. Did you see it?eLife · 2025
    Article
  16. Article
  17. Review
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  19. The multiple generator hypothesis of consciousness.Neuroscience of consciousness · 2025
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Itay YaronSagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel. itayyaron@mail.tau.ac.il.ORCID http://orcid.org/0000-0001-6299-765X
Lucia MelloniDepartment of Neurology, New York University Grossman School of Medicine, New York, NY, USA.ORCID http://orcid.org/0000-0001-8743-5071
Michael PittsDepartment of Psychology, Reed College, Portland, OR, USA.
Liad MudrikSagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding how consciousness arises from neural activity remains one of the biggest challenges for neuroscience. Numerous theories have been proposed in recent years, each gaining independent empirical support. Currently, there is no comprehensive, quantitative and theory-neutral overview of the field that enables an evaluation of how theoretical frameworks interact with empirical research. We provide a bird's eye view of studies that interpreted their findings in light of at least one of four leading neuroscientific theories of consciousness (N = 412 experiments), asking how methodological choices of the researchers might affect the final conclusions. We found that supporting a specific theory can be predicted solely from methodological choices, irrespective of findings. Furthermore, most studies interpret their findings post hoc, rather than a priori testing critical predictions of the theories. Our results highlight challenges for the field and provide researchers with an open-access website ( https://ContrastDB.tau.ac.il ) to further analyse trends in the neuroscience of consciousness.

Indexed as

ConsciousnessNeurosciencesEmpirical ResearchHumans

Identifiers

PMID35190711

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.