Evidence map›Paper›PMID 35190584›Full record

ArticleScientific reports2022

Predictors of cardiopulmonary fitness in cancer-affected and -unaffected women with a pathogenic germline variant in the genes BRCA1/2 (LIBRE-1).

A Berling-Ernst, M Yahiaoui-Doktor, M Kiechle, C Engel, J Lammert, S Grill, R Dukatz, K Rhiem, F T Baumann, S C Bischoff and 5 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06672120 (Exercise in Regional Breast Cancer With Neoadjuvant Anthracycline- Based Chemotherapy and Immunotherapy With Checkpoint-Inhibition), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06672120 narecruitingnot on this mapstarted 2025, after this paper: background citation

Exercise in Regional Breast Cancer With Neoadjuvant Anthracycline- Based Chemotherapy and Immunotherapy With Checkpoint-Inhibition

TypeinterventionalSponsorTechnical University of MunichRan2025 to 2028Enrolled120ConditionsCancer, BreastArmsExercise training
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

A Berling-Ernst *Department of Prevention and Sports Medicine, School of Medicine, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany. anika.berling-ernst@mri.tum.de.
M Yahiaoui-Doktor *Institute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.
M KiechleDepartment of Gynecology and Center for Hereditary Breast and Ovarian Cancer, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
C EngelInstitute for Medical Informatics, Statistics and Epidemiology (IMISE), University of Leipzig, Leipzig, Germany.
J LammertDepartment of Gynecology and Center for Hereditary Breast and Ovarian Cancer, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
S GrillDepartment of Gynecology and Center for Hereditary Breast and Ovarian Cancer, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
R DukatzDepartment of Gynecology and Center for Hereditary Breast and Ovarian Cancer, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
K RhiemCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), University Hospital Cologne, Cologne, Nordrhein-Westfalen, Germany.
F T BaumannCenter for Familial Breast and Ovarian Cancer, Center for Integrated Oncology (CIO), University Hospital Cologne, Cologne, Nordrhein-Westfalen, Germany.
S C BischoffInstitute of Nutritional Medicine, University of Hohenheim, Stuttgart, Germany.
N EricksonComprehensive Cancer Center Ludwig Maximillian University (CCC LMU), University of Munich Clinic, Campus Großhadern, Munich, Germany.
T SchmidtUniversity Cancer Center Schleswig-Holstein (UCCSH), Kiel, Germany.
U NiederbergerInstitute of Medical Psychology and Medical Sociology, University Medical Center Schleswig Holstein, Kiel, Germany.
M Siniatchkin *Institute of Medical Psychology and Medical Sociology, University Medical Center Schleswig Holstein, Kiel, Germany.
M Halle *Department of Prevention and Sports Medicine, School of Medicine, University Hospital Rechts der Isar, Technical University of Munich (TUM), Munich, Germany.
Klinikum rechts der Isar · DELeipzig University · DETechnical University of Munich · DEUniversity Hospital Cologne · DEUniversity Hospital Schleswig-Holstein · DELudwig-Maximilians-Universität München · DEUniversity Cancer Center Hamburg · DEUniversity of Hohenheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical activity (PA) helps prevention and aftercare of sporadic breast cancer (BC), cardiopulmonary fitness (CPF) being an age-independent predictor of tumor-specific mortality. Therefore, we wanted to identify predictors of CPF (represented by peak oxygen uptake: VO

Indexed as

Attitude to HealthExercise TestGerm-Line MutationOxygen ConsumptionAdultBRCA1 ProteinBRCA2 ProteinBreast NeoplasmsCross-Sectional StudiesExerciseFemaleHeterozygoteHumansMiddle AgedProspective StudiesSurveys and QuestionnairesBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA2 protein, human

Identifiers

PMID35190584
PMCPMC8861033
OpenAlexW4212936976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.