Evidence map›Paper›PMID 35190414›Full record

Trial reportBMJ open2022

Effectiveness of the Strengthening Families Programme in the UK at preventing substance misuse in 10-14 year-olds: a pragmatic randomised controlled trial.

Jeremy Segrott, David Gillespie, Mandy Lau, Jo Holliday, Simon Murphy, David Foxcroft, Kerenza Hood, Jonathan Scourfield, Ceri Phillips, Zoe Roberts and 3 more

Abstract readPragmatic Clinical TrialRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jeremy SegrottCentre for Trials Research, Cardiff University, Cardiff, UK SegrottJ@cardiff.ac.uk.ORCID 0000-0001-6215-0870
David GillespieCentre for Trials Research, Cardiff University, Cardiff, UK.ORCID 0000-0002-6934-2928
Mandy LauCentre for Trials Research, Cardiff University, Cardiff, UK.ORCID 0000-0001-5894-570X
Jo HollidayNuffield Department of Population Health, University of Oxford, Oxford, UK.ORCID 0000-0003-4568-7320
Simon MurphyDECIPHer Centre, School of Social Sciences, Cardiff University, Cardiff, UK.ORCID 0000-0003-3589-3681
David FoxcroftDepartment of Psychology, Health and Professional Development, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, UK.ORCID 0000-0001-9752-7527
Kerenza HoodCentre for Trials Research, Cardiff University, Cardiff, UK.ORCID 0000-0002-5268-8631
Jonathan ScourfieldChildren's Social Care Research and Development Centre (CASCADE), School of Social Sciences, Cardiff University, Cardiff, UK.ORCID 0000-0001-6218-8158
Ceri PhillipsCollege of Human and Health Sciences, Swansea University, Swansea, UK.ORCID 0000-0003-1076-9289
Zoe RobertsCentre for Medical Education, School of Medicine, Cardiff University, Cardiff, UK.
Heather RothwellDECIPHer Centre, School of Social Sciences, Cardiff University, Cardiff, UK.
Claire HurlowSwansea Trials Unit, Swansea University Medical School, Swansea University, Swansea, UK.
Laurence MooreMRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK.ORCID 0000-0003-2182-823X

Funding

Chief Scientist Office SPHSU14Medical Research Council G0802128Medical Research Council MC_UU_00022/1Medical Research Council MC_UU_12017/14Medical Research Council MR/K023233/1Medical Research Council MR/L002787/1Wellcome Trust
6 · The paper itself

Abstract

objectivesThe Strengthening Families Programme 10-14 (SFP10-14) is a USA-developed universal group-based intervention aiming to prevent substance misuse by strengthening protective factors within the family. This study evaluated a proportionate universal implementation of the adapted UK version (SFP10-14UK) which brought together families identified as likely/not likely to experience/present challenges within a group setting.

designPragmatic cluster-randomised controlled effectiveness trial, with families as the unit of randomisation and embedded process and economic evaluations.

settingThe study took place in seven counties of Wales, UK.

participants715 families (919 parents/carers, 931 young people) were randomised.

interventionsFamilies randomised to the intervention arm received the SFP10-14 comprising seven weekly sessions. Families in intervention and control arms received existing services as normal. OUTCOME MEASURES: Primary outcomes were the number of occasions young people reported drinking alcohol in the last 30 days; and drunkenness during the same period, dichotomised as 'never' and '1-2 times or more'. Secondary outcomes examined alcohol/tobacco/substance behaviours including: cannabis use; weekly smoking (validated by salivary cotinine measures); age of alcohol initiation; frequency of drinking >5 drinks in a row; frequency of different types of alcoholic drinks; alcohol-related problems. Retention: primary analysis included 746 young people (80.1%) (alcohol consumption) and 732 young people (78.6%) (drunkenness).

resultsThere was no evidence of statistically significant between-group differences 2 years after randomisation for primary outcomes (young people's alcohol consumption in the last 30 days adjusted OR=1.11, 95% CI 0.72 to 1.71, p=0.646; drunkenness in the last 30 days adjusted OR=1.46, 95% CI 0.83 to 2.55, p=0.185). There were no statistically significant between-group differences for other substance use outcomes, or those relating to well-being/stress, and emotional/behavioural problems.

conclusionsPrevious evidence of effectiveness was not replicated. Findings highlight the importance of evaluating interventions when they are adapted for new settings. TRIAL REGISTRATION NUMBER: ISRCTN63550893.Cite Now.

Indexed as

Alcoholic IntoxicationSubstance-Related DisordersAdolescentChildCost-Benefit AnalysisHumansParentsUnited Kingdomcommunity child healthpublic healthsubstance misuse

Identifiers

PMID35190414
PMCPMC8862464

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.