Evidence map›Paper›PMID 35190372›Full record

ArticleHeart (British Cardiac Society)2022

Association between age at onset of overweight and risk of hypertension across adulthood.

Weijian Li, Wei Fang, Zegui Huang, Xianxuan Wang, Zefeng Cai, Guanzhi Chen, Weiqiang Wu, Zhichao Chen, Shouling Wu, Youren Chen

Abstract read
In one paragraph

Article in Heart (British Cardiac Society), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Weijian LiShantou University Medical College, Shantou, China.ORCID 0000-0003-1774-8368
Wei FangShantou University Medical College, Shantou, China.
Zegui HuangShantou University Medical College, Shantou, China.
Xianxuan WangShantou University Medical College, Shantou, China.
Zefeng CaiDepartment of Cardiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Guanzhi ChenChina Medical University, Shenyang, China.
Weiqiang WuDepartment of Cardiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Zhichao ChenDepartment of Cardiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, China.
Shouling WuDepartment of Cardiology, Kailuan General Hospital, Tangshan, China 13902779840@139.com drwusl@163.com.ORCID 0000-0001-7095-6022
Youren ChenDepartment of Cardiology, Second Affiliated Hospital of Shantou University Medical College, Shantou, China 13902779840@139.com drwusl@163.com.ORCID 0000-0002-4060-3725

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to examine the association between age at onset of overweight and incident hypertension.

methodsWe analysed 4742 participants with new-onset overweight from the Kailuan study between 2006 and 2015 and and 4742 age-matched and sex-matched controls selected randomly from the same cohort but with normal weight. Participants were compared with respect to subsequent risk of hypertension, with sub-HR calculated with the Fine and Gray model, according to age of onset of overweight.

resultsOver a mean follow-up period of 5.17 years, 1642 overweight participants (34.6%) and 1293 normal-weight controls (27.3%) were subsequently diagnosed with hypertension. The median age at onset of overweight was 49.1 years. Compared with normal-weight controls, the multivariable-adjusted sub-HR for hypertension among participants with onset of overweight at 18-39 years of age, 40-49 years of age, 50-59 years of age and ≥60 years of age was 1.38 (95% CI 1.11 to 1.72), 1.27 (95% CI 1.09 to 1.49), 1.23 (95% CI 1.09 to 1.38) and 1.14 (95% CI 0.99 to 1.32), respectively. Onset of overweight in each age range was significantly associated with increased risk of hypertension, except for the group with onset at ≥60 years of age. The risk increased with each decade of attenuation of age at onset, peaking at 18-39 years of age.

conclusionsYounger age at onset of overweight across adulthood was associated with significantly increased risk of hypertension, with the highest relative risk among participants with onset of overweight at 18-39 years of age.

Indexed as

HypertensionOverweightAdolescentAdultAge of OnsetBody Mass IndexFemaleHumansMaleMiddle AgedObesityRisk FactorsYoung Adultepidemiologyhypertensionrisk factors

Identifiers

PMID35190372
PMCPMC8995813

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.