Evidence map›Paper›PMID 35190206›Full record

ArticleVaccine2022

Estimating the cost of COVID-19 vaccine deployment and introduction in Ghana using the CVIC tool.

Justice Nonvignon, Richmond Owusu, Brian Asare, Alex Adjagba, Yap Wei Aun, Karene Hoi Ting Yeung, Joycelyn Naa Korkoi Azeez, Martha Gyansa-Lutterodt, Godwin Gulbi, Kwame Amponsa-Achiano and 6 more

Abstract read
In one paragraph

Article in Vaccine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Justice NonvignonDepartment of Health Policy, Planning and Management, School of Public Health, University of Ghana, Legon, Ghana. Electronic address: jnonvignon@ug.edu.gh.
Richmond OwusuDepartment of Health Policy, Planning and Management, School of Public Health, University of Ghana, Legon, Ghana. Electronic address: riowusu@ug.edu.gh.
Brian AsareMinistry of Health, PMB, Accra, Ghana.
Alex AdjagbaHealth Section, UNICEF, 3 UN Plaza, New York, NY 10017, USA. Electronic address: aadjagba@unicef.org.
Yap Wei AunQuanticlear Solutions, Malaysia. Electronic address: weiaun@quanticlear.com.
Karene Hoi Ting YeungDepartment of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland. Electronic address: yeungh@who.int.
Joycelyn Naa Korkoi AzeezMinistry of Health, PMB, Accra, Ghana.
Martha Gyansa-LutterodtMinistry of Health, PMB, Accra, Ghana.
Godwin GulbiMinistry of Health, PMB, Accra, Ghana.
Kwame Amponsa-AchianoExpanded Programme on Immunization, Ghana Health Service, Accra, Ghana.
Frederick DadzieExpanded Programme on Immunization, Ghana Health Service, Accra, Ghana. Electronic address: jfdadzie@yahoo.co.uk.
George E ArmahNoguchi Memorial Institute for Medical Research, University of Ghana, Accra, Ghana. Electronic address: GArmah@noguchi.ug.edu.gh.
Logan BrenzelBill & Melinda Gates Foundation, Seattle, WA, USA. Electronic address: Logan.Brenzel@gatesfoundation.org.
Raymond HutubessyDepartment of Immunization, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland. Electronic address: hutubessyr@who.int.
Stephen C ReschCenter for Health Decision Science, Harvard T.H. Chan School of Public Health, 718 Huntington Ave., Boston, MA 02115, USA. Electronic address: stephen_resch@harvard.edu.
Ghana Health Technology Assessment Technical Working GroupMinistry of Health, PMB, Accra, Ghana.

Funding

World Health Organization 001
6 · The paper itself

Abstract

backgroundThis study estimated cost of COVID-19 vaccine introduction and deployment in Ghana.

methodsUsing the WHO-UNICEF COVID-19 Vaccine Introduction and deployment Costing (CVIC) tool Ghana's Ministry of Health Technical Working Group for Health Technology Assessment (TWG-HTA) in collaboration with School of Public Health, University of Ghana, organized an initial two-day workshop that brought together partners to deliberate and agree on input parameters to populate the CVIC tool. A further 2-3 days validation with the Expanded Program of Immunization (EPI) and other partners to finalize the analysis was done. Three scenarios, with different combinations of vaccine products and delivery modalities, as well as time period were analyzed. The scenarios included AstraZeneca (40%), Johnson & Johnson (J&J) (30%), Moderna, Pfizer, and Sputnik V at 10% each; with primary schedule completed by second half of 2021 (Scenario 1); AstraZeneca (30%), J&J (40%), Moderna, Pfizer, and Sputnik V at 10% each with primary schedule completed by first half of 2022 (Scenario 2); and equal distribution (20%) among AstraZeneca, J&J, Moderna, Pfizer, and Sputnik V with primary schedule completed by second half of 2022 (Scenario 3).

resultsThe estimated total cost of COVID-19 vaccination ranges between $348.7 and $436.1 million for the target population of 17.5 million. These translate into per person completed primary schedule cost of $20.9-$26.2 and per dose (including vaccine cost) of $10.5-$13.1. Again, per person completed primary schedule excluding vaccine cost was $4.5 and $4.6, thus per dose excluding vaccine also ranged from $2.2 - $2.3. The main cost driver was vaccine doses, including shipping, which accounts for between 78% and 83% of total cost. Further, an estimated 8,437-10,247 vaccinators (non-FTEs) would be required during 2021-2022 to vaccinate using a mix of delivery strategies, accounting for 8-10% of total cost.

conclusionThese findings provide the estimates to inform resource mobilization efforts by government and other partners.

Indexed as

COVID-19COVID-19 VaccinesGhanaHumansImmunization ProgramsSARS-CoV-2COVID-19 VaccinesCostsCOVID-19 vaccineCVIC toolGhana

Identifiers

PMID35190206
PMCPMC8813551

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.