ReviewJournal of biomedical science2022
The pathogenic effects of particulate matter on neurodegeneration: a review.
Review in Journal of biomedical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- A systematic review with a Burden of Proof meta-analysis of health effects of long-term ambient fine particulate matter (PMNature aging · 2025Pooled it
- Quantifying the association between PMEnvironmental health : a global access science source · 2024Pooled it
- PMEnvironmental health perspectives · 2026Article
- Urban PMMolecular neurobiology · 2026Article
- Long-term cumulative associations of annual air pollution exposure and hospitalization with Parkinson's Disease.Environmental epidemiology (Philadelphia, Pa.) · 2026Article
- Article
- Ambient particulate matters are associated with attenuation or reversal of positive association between Folate and cognitive function in Chinese older adults.BMC public health · 2026Article
- Prenatal exposure to particulate matter impairs offspring behavior via hippocampal NMDA receptor reduction: an in vivo and ex vivo study.Environment international · 2026Article
- Children's respiratory hospitalizations linked to short-term air pollution exposure in Peninsular Malaysia's urban areas.Scientific reports · 2026Article
- The Impact of Chemical Toxicants and Air Pollutants on Neurodegenerative Disorders and Their Underlying Potential Mechanisms: A Literature Review.Health science reports · 2026Article
- Association between traffic-related air pollution and brain morphology, assessing the olfactory pathway as a mediator.Brain communications · 2026Article
- Topological modelling of urban air pollution and cognition.npj digital public health · 2026Article
- A comprehensive approach for detecting and locating black carbon in human placentae.Air quality, atmosphere, & health · 2026Article
- Investigating the Potential Roles of Environmental Exposures on the Pathology of Amyotrophic Lateral Sclerosis by Overlap Analysis.Neurotoxicity research · 2025Article
- Ambient Air Pollution and the Severity of Alzheimer Disease Neuropathology.JAMA neurology · 2025Article
- Metabolome informs about the chemical exposome and links to brain health.Environment international · 2025Review
- The cognitive toll of household air pollution: cross-sectional associations between polluting cooking fuel use, cognitive functions and brain MRI in a rural aging population from Karnataka, India.The Lancet regional health. Southeast Asia · 2025Article
- Impact of air pollution and occupational inhalation exposures on neurodegenerative disorders: An epigenetic perspective.iScience · 2025Review
- Assessment of Individual Exposure to Multiple Pollutants (Noise, Particulate Matter, and Extremely Low-Frequency Magnetic Fields) Related to Daily Life Microenvironments in the Brussels Capital Region: Protocol for a Cross-Sectional Study.JMIR research protocols · 2025Article
- The role of the components of PMEnvironment international · 2025Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The increasing amount of particulate matter (PM) in the ambient air is a pressing public health issue globally. Epidemiological studies involving data from millions of patients or volunteers have associated PM with increased risk of dementia and Alzheimer's disease in the elderly and cognitive dysfunction and neurodegenerative pathology across all age groups, suggesting that PM may be a risk factor for neurodegenerative diseases. Neurodegenerative diseases affect an increasing population in this aging society, putting a heavy burden on economics and family. Therefore, understanding the mechanism by which PM contributes to neurodegeneration is essential to develop effective interventions. Evidence in human and animal studies suggested that PM induced neurodenegerative-like pathology including neurotoxicity, neuroinflammation, oxidative stress, and damage in blood-brain barrier and neurovascular units, which may contribute to the increased risk of neurodegeneration. Interestingly, antagonizing oxidative stress alleviated the neurotoxicity of PM, which may underlie the essential role of oxidative stress in PM's potential effect in neurodegeneration. This review summarized up-to-date epidemiological and experimental studies on the pathogenic role of PM in neurodegenerative diseases and discussed the possible underlying mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.