Evidence map›Paper›PMID 35189849›Full record

Observational studyBMC ophthalmology2022

Quantification of an oval optic disc in relation to myopic foveoschisis using swept-source optical coherence tomography.

Ke Zhu, Boya Lei, Keyan Wang, Fang Song, Rui Jiang, Qing Chang, Gezhi Xu, Han Chen

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Relationship between the structure and microcirculation of the optic disc region and myopic traction maculopathy in highly myopic eyes.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ke ZhuEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Boya LeiEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Keyan WangEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Fang SongEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Rui JiangEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Qing ChangEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Gezhi XuEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, 83 Fen Yang Road, Shanghai, 200031, China.
Han ChenEye Institute and Department of Ophthalmology, Eye and ENT Hospital, Fudan University, 83 Fen Yang Road, Shanghai, 200031, China. hancheneent@163.com.
Eye & ENT Hospital of Fudan University · CNFudan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the relationship between an oval optic disc and the occurrence of myopic foveoschisis (MF) using swept-source optic coherence tomography (SS-OCT).

methodsFifty eyes of 25 patients with unilateral MF were included in this retrospective observational study. The biometric features of the optic disc and peripapillary structures were evaluated using SS-OCT.

resultsThe ovality index (OI) of the optic disc was significantly smaller (P = 0.003) and the optic disc tilt angle was greater (P = 0.023) in the eyes with MF than in the contralateral eyes. The optic disc tilt angle was significantly correlated with the OI (P = 0.000). Generalized estimating equation (GEE) model (linear regression) demonstrated that spherical equivalent refraction (P = 0.001), narrow macular staphyloma (P = 0.001) and the occurrence of MF (P = 0.026) were the independent factors associated with the OI. Narrow macular staphyloma was more frequent (P = 0.020) and the staphyloma was deeper (P = 0.006) in eyes with MF. GEE model (logistic regression) revealed that narrow macular staphyloma was the only independent factor related to the occurrence of MF (P = 0.013).

conclusionsAn oval optic disc in eyes with MF resulted from the increased tilt around the vertical disc axis. The optic disc tilt was related to narrow macular staphyloma, which was the only independent factor associated with the occurrence of MF. The clinical relevance needs further exploration through longitudinal analysis.

Indexed as

MyopiaOptic DiskBiometryHumansRefraction, OcularTomography, Optical CoherenceMyopic foveoschisisNarrow macular staphylomaOptic disc tiltOval optic discSwept-source optic coherence tomography

Identifiers

PMID35189849
PMCPMC8862570
OpenAlexW4213117691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.