Evidence map›Paper›PMID 35189711›Full record

ArticleCirculation research2022

Readily Available Tissue-Engineered Vascular Grafts Derived From Human Induced Pluripotent Stem Cells.

Jiesi Luo, Lingfeng Qin, Jinkyu Park, Mehmet H Kural, Yan Huang, Xiangyu Shi, Muhammad Riaz, Juan Wang, Matthew W Ellis, Christopher W Anderson and 6 more

Abstract readLetter
In one paragraph

Article in Circulation research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Artificial blood vessels-clinical development of TEVG.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Review
  3. Article
  4. Towards advanced regenerative therapeutics to tackle cardio-cerebrovascular diseases.American heart journal plus : cardiology research and practice · 2025
    Review
  5. Review
  6. Biomimetic fabricated tubular graftBioactive materials · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jiesi Luo *Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, U.S.A. (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., Y.Q.).ORCID 0000-0002-3041-7283
Lingfeng Qin *Surgery (L.Q., G.T.).
Jinkyu Park *Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, U.S.A. (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., Y.Q.).
Mehmet H Kural *Anesthesiology (M.H.K., J.W., Y.Y., L.E.N.).
Yan HuangYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, U.S.A. (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., Y.Q.).
Xiangyu ShiYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, U.S.A. (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., Y.Q.).
Muhammad RiazYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, U.S.A. (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., Y.Q.).ORCID 0000-0002-0311-8392
Juan WangAnesthesiology (M.H.K., J.W., Y.Y., L.E.N.).ORCID 0000-0003-0219-4200
Matthew W EllisYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, U.S.A. (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., Y.Q.).
Christopher W AndersonYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, U.S.A. (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., Y.Q.).
Yifan YuanAnesthesiology (M.H.K., J.W., Y.Y., L.E.N.).
Yongming RenYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, U.S.A. (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., Y.Q.).
Mervin C YoderIndiana Center for Regenerative Medicine and Engineering, Indiana University School of Medicine, Indianapolis, IN, U.S.A. (M.C.Y.).ORCID 0000-0003-4354-7631
George TellidesSurgery (L.Q., G.T.).
Laura E NiklasonYale Stem Cell Center (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., L.E.N., Y.Q.).
Yibing QyangYale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, U.S.A. (J.L., J.P., Y.H., X.S., M.R., M.W.E., C.W.A., Y.R., Y.Q.).ORCID 0000-0002-0332-2449

Funding

INSTITUTIONAL NATIONAL RESEARCH SERVICE AWARDT32GM007324 · NIGMS · YALE UNIVERSITY · PI BENNETT, ANTON M · 1987 to 2022
$6.2M
Readily Available Stem Cell-Based Vascular Grafts for Emergent Surgical CareR01HL150352 · NHLBI · YALE UNIVERSITY · PI QYANG, YIBING · 2020 to 2023
$2.8M
Biologically Selective Drug-Eluting StentR01HL148819 · NHLBI · YALE UNIVERSITY · PI SALTZMAN, WILLIAM · 2019 to 2022
$2.7M
Human tissue-engineered blood vessels using induced pluripotent stem cellsR01HL116705 · NHLBI · YALE UNIVERSITY · PI QYANG, YIBING · 2013 to 2017
$2.0M
Development of HLA engineered universal vascular grafts from human iPSCsR01HL155411 · NHLBI · YALE UNIVERSITY · PI QYANG, YIBING · 2021 to 2024
$1.7M
Reconstructing native soluble cues in vascularized whole lung scaffoldsR00HL159261 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI YUAN, YIFAN · 2023 to 2025
$747k
Reconstructing native soluble cues in vascularized whole lung scaffoldsK99HL159261 · NHLBI · YALE UNIVERSITY · PI YUAN, YIFAN · 2022 to 2023
$245k
HUMAN TISSUE ENGINEERED PULSATILE CONDUITS USING ENGINEERED HEART TISSUE OF DEFINED COMPOSITION AND FIBER ORIENTATIONF31HL143928 · NHLBI · YALE UNIVERSITY · PI ANDERSON, CHRISTOPHER W · 2018 to 2020
$135k
Biomechanical Signaling in Vascular Smooth Muscle Cell Proliferative Disease Following Functional Loss of ElastinF31HL143924 · NHLBI · YALE UNIVERSITY · PI ELLIS, MATTHEW W · 2019 to 2020
$91k
NHLBI NIH HHS F31 HL143924NHLBI NIH HHS F31 HL143928NHLBI NIH HHS K99 HL159261NHLBI NIH HHS R00 HL159261NHLBI NIH HHS R01 HL116705NHLBI NIH HHS R01 HL148819NHLBI NIH HHS R01 HL150352NHLBI NIH HHS R01 HL155411NIGMS NIH HHS T32 GM007324
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Induced Pluripotent Stem CellsBlood Vessel ProsthesisCell DifferentiationHumansTissue EngineeringTissue Scaffoldsendothelial cellsinduced pluripotent stem cellstissue engineeringtransplantation

Identifiers

PMID35189711
PMCPMC9113663

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.