Trial reportDigestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society2022
Prevalence of missed lesions in patients with inadequate bowel preparation through a very early repeat colonoscopy.
Trial report in Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- A meta-analysis of the safety and efficacy of 2 L versus 3 L polyethylene glycol in bowel preparation for colonoscopy.BMC gastroenterology · 2026Pooled it
- Risk prediction models for inadequate bowel preparation before colonoscopy: A systematic review and meta-analysis.PloS one · 2026Pooled it
- Linaclotide combined with polyethylene glycol for bowel preparation in colonoscopy: a systematic review and meta-analysis of randomized controlled trials.Surgical endoscopy · 2026Pooled it
- Article
- To what extent can bowel preparation quality be considered "adequate"?: a systematic review and meta-analysis.Clinical endoscopy · 2026Article
- Investigating the Association Between Cystic Fibrosis and Colorectal Neoplasia: A Matched Case-Control Study.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- The Clinical Importance of Adequate Bowel Preparation.Alimentary pharmacology & therapeutics · 2026Review
- Impact of glucagon-like peptide-1 receptor agonists on colonoscopy outcomes: a systematic review and meta-analysis.Clinical endoscopy · 2026Article
- Efficacy and acceptability of bowel preparation strategies for inflammatory bowel disease colonoscopy: Systematic review and meta-analysis.Endoscopy international open · 2026Article
- Development and validation of a gut motility based model for predicting bowel preparation quality.Scientific reports · 2025Article
- Prospective validation of the Barcelona scale for the assessment of mucosal cleanliness during upper gastrointestinal endoscopy.Therapeutic advances in gastroenterology · 2025Article
- Efficacy and safety of lubiprostone combined with polyethylene glycol electrolyte powder for bowel preparation in patients classified by risk level: a randomised trial.Frontiers in oncology · 2025Article
- Impact of WeChat guidance on bowel preparation for colonoscopy: a quasi-experiment study.Scientific reports · 2023Article
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Authors and funding
21 authors at 12 institutions in 1 country.
Funding
Abstract
objectivesWhen bowel preparation (BP) is inadequate, international guidelines recommend repeating the colonoscopy within 1 year to avoid missing clinically relevant lesions. We aimed to determine the rate of missed lesions in patients with inadequate BP through a very early repeat colonoscopy with adequate BP.
methodsPost hoc analysis was conducted using data collected from a prospective multicenter randomized clinical trial including patients with inadequate BP and then repeat colonoscopy. Inadequate BP was defined as the Boston Bowel Preparation Scale (BBPS) score <2 points in any segment. We included patients with any indication for colonoscopy. The adenoma detection rate (ADR), advanced ADR (AADR), and serrated polyp detection rate (SPDR) were calculated for index and repeat colonoscopies.
resultsOf the 651 patients with inadequate BP from the original trial, 413 (63.4%) achieved adequate BP on repeat colonoscopy. The median interval between index and repeat colonoscopies was 28 days. On repeat colonoscopy, the ADR was 45.3% (95% confidence interval [CI] 40.5-50.1%), the AADR was 10.9% (95% CI 8.1-14.3%), and the SPDR was 14.3% (95% CI 10.9-17.7%). Cancer was discovered in four patients (1%; 95% CI 0.2-2.5%). A total of 60.2% of all advanced adenoma (AA) were discovered on repeat colonoscopy. A colon segment scored BBPS = 0 had most AA (66.1%) and all four cancers.
conclusionPatients with inadequate BP present a high rate of AAs on repeat colonoscopy. When a colonoscopy has a colon segment score BBPS = 0, we recommend repeating the colonoscopy as soon as possible.
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