Evidence map›Paper›PMID 35188975›Full record

ArticleThe Laryngoscope2022

Gustatory Function in Acute COVID-19 - Results From Home-Based Psychophysical Testing.

Constantin A Hintschich, Anja Brosig, Thomas Hummel, Kornelia E Andorfer, Jürgen J Wenzel, Christopher Bohr, Veronika Vielsmeier

Abstract read
In one paragraph

Article in The Laryngoscope, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Limited observed efficacy of olfactory training in severe long-term post-COVID-19 syndrome: a prospective cohort study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Author's reply to the Letter to the Editor "The study of olfactory dysfunction in SARS-CoV-2 variants".European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  7. Objective Evaluation of Smell and Taste Senses in COVID-19 Patients.Turkish archives of otorhinolaryngology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Constantin A HintschichDepartment of Otorhinolaryngology, Regensburg University Hospital, Regensburg, Germany.ORCID 0000-0002-5500-600X
Anja BrosigDepartment of Otorhinolaryngology, Regensburg University Hospital, Regensburg, Germany.
Thomas HummelSmell & Taste Clinic, Department of Otorhinolaryngology, TU Dresden, Dresden, Germany.ORCID 0000-0001-9713-0183
Kornelia E AndorferDepartment of Otorhinolaryngology, Regensburg University Hospital, Regensburg, Germany.
Jürgen J WenzelInstitute of Clinical Microbiology and Hygiene, Regensburg University Hospital, Regensburg, Germany.
Christopher BohrDepartment of Otorhinolaryngology, Regensburg University Hospital, Regensburg, Germany.
Veronika VielsmeierDepartment of Otorhinolaryngology, Regensburg University Hospital, Regensburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGustatory function during COVID-19 is self-reported by around 50% of patients. However, only a few studies assessed gustation using psychophysical testing during acute infection. The objective of this study is to test gustatory function on threshold tests in the very first days of COVID-19.

methodsPsychophysical testing consisted of validated and blinded tests for olfaction (NHANES Pocket Smell Test) and gustation (Taste Strips Test). These test kits were sent to home-quarantined patients and self-administered using a detailed instruction sheet.

resultsA total of 51 patients were included in this study. Testing was performed 6.5 ± 2.7 days after sampling of respiratory swabs. At this time 37% of patients stated to currently experience a gustatory impairment. The mean Taste Strips score was 10.0 ± 3.4 with 28% scoring in the range of hypogeusia. Interestingly, no significant difference in the results of gustatory testing could be observed between the group with subjectively preserved gustation and the group with self-rated taste impairment.

conclusionDuring the very first days of COVID-19, psychophysical gustatory testing revealed hypogeusia in 28%. This is far lower than patients' self-reports. Different from previous studies, we did not find clear evidence for an impairment of only certain taste qualities. LEVEL OF EVIDENCE: 3 Laryngoscope, 132:1082-1087, 2022.

Indexed as

AgeusiaCOVID-19Olfaction DisordersDysgeusiaHumansNutrition SurveysSmellTasteTaste DisordersCOVID-19gustationolfactionpsychophysical testssmelltaste

Identifiers

PMID35188975
PMCPMC9088467

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.