Evidence map›Paper›PMID 35188880›Full record

ArticleSubstance use & misuse2022

Relationships among Substance Use, Sociodemographics, Pre-Exposure Prophylaxis (PrEP) Awareness and Related Attitudes among Young Adult Men Who Have Sex with Men.

Nioud Mulugeta Gebru, Maria Costanza Benvenuti, Bonnie H P Rowland, Meher Kalkat, Patricia G Chauca, Robert F Leeman

Registry-linked trialAbstract read
In one paragraph

Article in Substance use & misuse, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06676059 (SMART-r), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06676059 recruitingnot on this mapstarted 2026, after this paper: background citation

SMART-r: Substance Monitoring and Active Relapse Tracking Repository

TypeobservationalSponsorNational Institute on Drug Abuse (NIDA)Ran2026 to 2044Enrolled10,000ConditionsAlcoholism, Substance-Related Disorders
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. An Evidence-Based Approach to Facilitating PrEP Initiation Among YMSM: The MyPEEPS Plus mHealth and E-Peer Navigation Intervention.AIDS education and prevention : official publication of the International Society for AIDS Education · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Use of preexposure prophylaxis and condom purchasing decisions.Journal of the experimental analysis of behavior · 2024
    Article
  8. Retrospective audit of a convenience cohort of individuals on HIV pre-exposure prophylaxis in Alberta, Canada.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2022
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nioud Mulugeta GebruDepartment of Health Education & Behavior, College of Health & Human Performance; Center for Addiction Research and Education, University of Florida, Gainesville, Florida, USA.ORCID 0000-0002-9335-2667
Maria Costanza BenvenutiDepartment of Health Education & Behavior, College of Health & Human Performance; Center for Addiction Research and Education, University of Florida, Gainesville, Florida, USA.
Bonnie H P RowlandDepartment of Psychological and Brain Sciences, Boston University, Boston, Massachusetts, USA.
Meher KalkatDepartment of Health Education & Behavior, College of Health & Human Performance; Center for Addiction Research and Education, University of Florida, Gainesville, Florida, USA.
Patricia G ChaucaDepartment of Health Education & Behavior, College of Health & Human Performance; Center for Addiction Research and Education, University of Florida, Gainesville, Florida, USA.
Robert F LeemanDepartment of Health Education & Behavior, College of Health & Human Performance; Center for Addiction Research and Education, University of Florida, Gainesville, Florida, USA.

Funding

Translational Science Training to Reduce the Impact of Alcohol on HIV InfectionT32AA025877 · NIAAA · UNIVERSITY OF FLORIDA · PI Robert L Cook, DEBRA E LYON · 2018 to 2026
$3.3M
Using Behavioral Measures to Assess Change in HIV Sexual Risk-Taking Following Pre-Exposure Prophylaxis (PrEP) Uptake in Heavy Drinking Young Men Who Have Sex With MenF31AA028751 · NIAAA · UNIVERSITY OF FLORIDA · PI GEBRU, NIOUD MULUGETA · 2020 to 2021
$85k
NIAAA NIH HHS F31 AA028751
6 · The paper itself

Abstract

Men who have sex with men (MSM) account for two-thirds of new HIV diagnoses. Pre-exposure prophylaxis (PrEP), a highly efficacious HIV preventive medication, is underutilized. Identifying correlates of PrEP awareness and attitudes may help increase PrEP use. Thus, we evaluated (1) PrEP awareness; (2) differences in awareness related to substance use and sociodemographics; (3) initial PrEP information sources; and (4) possible associations between information sources and PrEP-related attitudes. Young adult (ages 18-30) HIV-negative MSM from Southern U.S. undertook a web survey including questions about substance use, sexual behaviors, perceived HIV risk, and PrEP. Participants were recruited using in-person and online approaches between January 2018-January 2020. Of 506 participants, 89% were aware of PrEP. Participants with high alcohol consumption and greater perceived HIV risk had higher odds of PrEP unawareness with a trend for minority race/ethnicity. PrEP-aware participants reported high overall perceived safety, confidence in PrEP's efficacy, and low perceived difficulties with adherence though those with higher perceived HIV risk and individuals who used tobacco had less favorable attitudes. Most participants first heard about PrEP from the internet. There were no statistically significant differences in PrEP-related attitudes across initial information sources. Associations between substance use and racial/ethnic minority status and lack of PrEP awareness suggest priority subgroups for educational campaigns. Future campaigns may tailor outreach materials to the respective audience (e.g., Spanish materials for Hispanic people) and disseminate where individuals who use substances may be more likely to see them (e.g., liquor and convenience stores). Supplemental data for this article is available online at https://doi.org/10.1080/10826084.2022.2040030 .

Indexed as

HIV InfectionsPre-Exposure ProphylaxisSexual and Gender MinoritiesSubstance-Related DisordersAdolescentAdultEthnicityHealth Knowledge, Attitudes, PracticeHomosexuality, MaleHumansMaleMinority GroupsYoung AdultHIVinternetMSMPrEP beliefsSoutheastern U.S

Identifiers

PMID35188880
PMCPMC9082761

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.