Evidence map›Paper›PMID 35187889›Full record

ArticleJournal of Zhejiang University. Science. B2022

Upregulation of h-TERT and Ki-67 in ectopic endometrium is associated with recurrence of endometriosis.

Jie Luo, Zhimin Song, Tao Zhang, Ketan Chu, Jingyi Li, Jianhong Zhou, Jun Lin

Open access · greenAbstract read
In one paragraph

Article in Journal of Zhejiang University. Science. B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Endometriosis and the Hallmarks of Cancer.Reproductive sciences (Thousand Oaks, Calif.) · 2026
    Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jie LuoDepartment of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Zhimin SongDepartment of Obstetrics and Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Tao ZhangDepartment of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Ketan ChuDepartment of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Jingyi LiDepartment of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China.
Jianhong ZhouDepartment of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China. zhoujh1117@zju.edu.cn.
Jun LinDepartment of Gynecology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China. linjun@zju.edu.cn.
Women's Hospital, School of Medicine, Zhejiang University · CN

Funding

the Natural Science Foundation of Zhejiang Province LGF20H040009
6 · The paper itself

Abstract

At present, endometriosis remains a worldwide health burden, with the main symptoms of dysmenorrhea, chronic pelvic pain, and infertility, markedly reducing the quality of life (de Ziegler et al., 2010). Although there is no proof that the disease is associated with high mortality, this disorder can significantly contribute to the deterioration of women's general well-being (McPeak et al., 2018). The main current treatment for endometriosis is surgery to remove endometriotic lesions; however, the recurrence rate following surgical treatment is as high as 21.5% at two years and 40.0%‍-‍50.0% at five years post-surgery (Koga et al., 2015). To prevent recurrence, adjuvant treatment with drugs after surgery is recommended to prolong relapse-free intervals. However, it is inconvenient for patients to continuously use such medications in terms of adverse effects and cost (Turk, 2002).

Indexed as

EndometriosisEndometriumKi-67 AntigenTelomeraseFemaleHumansQuality of LifeRecurrenceUp-RegulationKi-67 AntigenMKI67 protein, humanTelomeraseTERT protein, human

Identifiers

PMID35187889
PMCPMC8861560
OpenAlexW4213158634

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.