ArticleJournal of Zhejiang University. Science. B2022
Index of microcirculatory resistance: state-of-the-art and potential applications in computational simulation of coronary artery disease.
Article in Journal of Zhejiang University. Science. B, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Angiography-based coronary microvascular assessment with and without intracoronary pressure measurements: a systematic review.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Pooled it
- Lumped-parameter model as a non-invasive tool to assess coronary blood flow in AAOCA patients.Scientific reports · 2023Trial
- The Contemporary Role of Intracoronary Physiological Assessment: Fractional Flow Reserve, Non-Hyperemic Pressure Ratios, Wireless Technologies, and Microcirculation.Journal of cardiovascular development and disease · 2026Review
- [Evaluation of coronary microvascular dysfunction for assessing prognosis of ST-segment elevation acute myocardial infarction following reperfusion therapy: insights from QFR-AMR].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Establishing Hemodynamic Convergence Framework for Coronary Digital Twins Under Realistic Dynamic Heart Rates.Physics of fluids (Woodbury, N.Y. : 1994) · 2025Article
- Coronary artery volume to left ventricular myocardial mass ratio in detecting primary microvascular angina: a retrospective observational study in Chinese population.BMC cardiovascular disorders · 2025Observational
- Coronary Microvascular Disease Early After Myocardial Infarction: Diagnostic Approach and Prognostic Value-A Narrative Review.Biomedicines · 2025Review
- Retinal Microvascular Characteristics-Novel Risk Stratification in Cardiovascular Diseases.Diagnostics (Basel, Switzerland) · 2025Article
- Identification of Coronary Morphological Damage in Patients with Chronic Inflammatory Rheumatic Diseases.Diagnostics (Basel, Switzerland) · 2025Article
- Chronic Coronary Artery Disease: Wall Disease vs. Lumenopathy.Biomolecules · 2025Review
- Diagnostic performance of multi-branch coronary angiography-based index of microcirculatory resistance: a novel approach.Frontiers in medicine · 2025Article
- Implementation of Microcirculation Examination in Clinical Practice-Insights from the Nationwide POL-MKW Registry.Medicina (Kaunas, Lithuania) · 2024Article
- Coronary Microvascular Dysfunction and Hypertension: A Bond More Important than We Think.Medicina (Kaunas, Lithuania) · 2023Review
- The Association of Severe Coronary Tortuosity and Non-Obstructive Coronary Artery Disease.Medicina (Kaunas, Lithuania) · 2023Article
- Prognostic Value of Post-PCI Angiography-Derived Fractional Flow Reserve: A Systematic Review and Meta-Analysis of Cohort Studies.Journal of personalized medicine · 2023Review
- Wearable Multisensor Ring-Shaped Probe for Assessing Stress and Blood Oxygenation: Design and Preliminary Measurements.Biosensors · 2023Article
- Coronary Artery Bypass Graft Surgery Brings Better Benefits to Heart Failure Hospitalization for Patients with Severe Coronary Artery Disease and Reduced Ejection Fraction.Diagnostics (Basel, Switzerland) · 2022Article
- The Continuum of Invasive Techniques for the Assessment of Intermediate Coronary Lesions.Diagnostics (Basel, Switzerland) · 2022Review
- Reliable Detection of Myocardial Ischemia Using Machine Learning Based on Temporal-Spatial Characteristics of Electrocardiogram and Vectorcardiogram.Frontiers in physiology · 2022Article
- Computational Pressure-Fluid Dynamics Applied to Index of Microcirculatory Resistance, Predicting the Prognosis of Drug-Coated Balloons Compared With Drug-Eluting Stents in STEMI Patients.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The dysfunction of coronary microcirculation is an important cause of coronary artery disease (CAD). The index of microcirculatory resistance (IMR) is a quantitative evaluation of coronary microcirculatory function, which provides a significant reference for the prediction, diagnosis, treatment, and prognosis of CAD. IMR also plays a key role in investigating the interaction between epicardial and microcirculatory dysfunctions, and is closely associated with coronary hemodynamic parameters such as flow rate, distal coronary pressure, and aortic pressure, which have been widely applied in computational studies of CAD. However, there is currently a lack of consensus across studies on the normal and pathological ranges of IMR. The relationships between IMR and coronary hemodynamic parameters have not been accurately quantified, which limits the application of IMR in computational CAD studies. In this paper, we discuss the research gaps between IMR and its potential applications in the computational simulation of CAD. Computational simulation based on the combination of IMR and other hemodynamic parameters is a promising technology to improve the diagnosis and guide clinical trials of CAD.
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