Evidence map›Paper›PMID 35187872›Full record

ArticleJournal of periodontal & implant science2022

Systemic and local effects of doxycycline and low-intensity laser treatment on periodontitis in rats.

Glauco Rodrigues Carmo Silveira, Daniela Coelho de Lima, Luciano Tavares Ângelo Cintra, Maísa Ribeiro Pereira Lima Brigagão, Edilson Ervolino, Leandro Araújo Fernandes

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of periodontal & implant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Glauco Rodrigues Carmo SilveiraFederal University of Alfenas (UNIFAL-MG) Faculty of Dentistry, Alfenas, Brazil.ORCID https://orcid.org/0000-0003-1926-819X
Daniela Coelho de LimaFederal University of Alfenas (UNIFAL-MG) Faculty of Dentistry, Alfenas, Brazil.ORCID https://orcid.org/0000-0002-7945-435X
Luciano Tavares Ângelo CintraDepartment of Restorative Dentistry, São Paulo State University (UNESP) Faculty of Dentistry, Araçatuba, Brazil.ORCID https://orcid.org/0000-0003-2348-7846
Maísa Ribeiro Pereira Lima BrigagãoDepartment of Biochemistry, Federal University of Alfenas (UNIFAL-MG) Faculty of Dentistry, Alfenas, Brazil.ORCID https://orcid.org/0000-0003-2346-082X
Edilson ErvolinoDepartment of Basic Sciences, São Paulo State University (UNESP) Faculty of Dentistry, Araçatuba, Brazil.ORCID https://orcid.org/0000-0003-4859-0583
Leandro Araújo FernandesFederal University of Alfenas (UNIFAL-MG) Faculty of Dentistry, Alfenas, Brazil. learaujofernandes@gmail.com.ORCID https://orcid.org/0000-0003-2227-5366
Universidade Federal de Alfenas · BRUniversidade Estadual Paulista (Unesp) · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível SuperiorPROCAD
6 · The paper itself

Abstract

purposeThis study evaluated the systemic and local effects of doxycycline (DOX) and low-intensity laser (LIL) treatment as adjuvants to scaling and root planing (SRP) in the treatment of experimental periodontitis in rats.

methodsThe sample consisted of 180 male rats (

resultsIn the intragroup analysis, lower concentrations of α-1-glycoprotein acid (α-1-Ga) and complement 3 (C3) were observed in the DOX+LIL group than in all other groups at all time points, as well as lower levels of complement 4 (C4) at 15 and 30 days (

conclusionsThe combination of DOX with LIL as SRP adjuvants was effective both systemically and locally for the treatment of experimental periodontitis in rats.

Indexed as

DoxycyclineLasersPeriodontal diseasePeriodontitisRats

Identifiers

PMID35187872
PMCPMC8860759
OpenAlexW3203097830

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.