Evidence map›Paper›PMID 35187723›Full record

SynthesisJournal of clinical laboratory analysis2022

COVID-19 in HIV-positive patients: A systematic review of case reports and case series.

Mohsen Heidary, Arezoo Asadi, Negar Noorbakhsh, Shirin Dashtbin, Parisa Asadollahi, Atieh Dranbandi, Tahereh Navidifar, Roya Ghanavati

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohsen HeidaryDepartment of Laboratory Sciences, School of Paramedical Sciences, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Arezoo AsadiDepartment of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Negar NoorbakhshBehbahan Faculty of Medical Sciences, Behbahan, Iran.
Shirin DashtbinDepartment of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Parisa AsadollahiMicrobiology Department, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.
Atieh DranbandiDepartment of Microbiology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Tahereh NavidifarShoushtar Faculty of Medical Sciences, Shoushtar, Iran.ORCID 0000-0003-4584-2327
Roya GhanavatiBehbahan Faculty of Medical Sciences, Behbahan, Iran.ORCID 0000-0002-3851-0001

Funding

Behbahan Faculty of Medical Sciences 400019
6 · The paper itself

Abstract

introductionCoronavirus disease 2019 (COVID-19) and acquired immune deficiency syndrome (AIDS) are two viral diseases for which there are currently no definitive treatments. Nowadays, because of the health system's focus on the COVID-19 epidemic, the control of human immunodeficiency virus (HIV) has received less attention. In this review, we will discuss the characteristics of COVID-19 in HIV-positive patients. MATERIAL AND

methodsUsing the PRISMA guideline, the databases of Scopus, PubMed, and Web of Science were searched systematically from January 1, 2019 to February 24, 2021. The following keywords were used: "Human Immunodeficiency Virus," "acquired immune deficiency syndrome," "HIV," "AIDS," "COVID-19," "severe acute respiratory syndrome coronavirus 2," "novel coronavirus," "SARS-CoV-2," "nCoV disease," "SARS2," and "2019-nCoV disease."

resultsTwenty-one percent of studies were conducted in the USA (n = 13), 16% in China (n = 10), and 13% in Italy (n = 8), respectively. The majority of the patients were men (74.3%). Tenofovir disoproxil fumarate was used in 47.4% of patients, emtricitabine in 58.4%, and lamivudine in 34.8% to treat HIV. Symptoms of HIV patients with COVID-19 included coughing (81.3%), fever (62.8%), and dyspnea (60%). Hydroxychloroquine (39.34%) and azithromycin (36.58%) were the common treatment options for COVID-19. The total death rate in HIV-positive patients with COVID-19 was about 9%.

conclusionIn the current systematic review, we demonstrated that HIV-positive patients co-infected with COVID-19 have high comorbidity of hypertension and diabetes mellitus. HIV/COVID-19 co-infection might have negatively influenced the HIV treatment and diagnosis, which indicates the need to regularly screen HIV patients in the COVID-19 pandemic.

Indexed as

Acquired Immunodeficiency SyndromeCOVID-19HIV InfectionsCase Reports as TopicFemaleHumansMalePandemicsSARS-CoV-2co-infectionCOVID-19HIVreview

Identifiers

PMID35187723
PMCPMC8993621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.