Evidence map›Paper›PMID 35187614›Full record

ArticleDrugs & aging2022

Barriers and Enablers of Healthcare Providers to Deprescribe Cardiometabolic Medication in Older Patients: A Focus Group Study.

Jamila Abou, Stijn Crutzen, Vashti Tromp, Mette Heringa, Rob Van Marum, Petra Elders, Katja Taxis, Petra Denig, Jacqueline Hugtenburg

Open access · hybridAbstract read
In one paragraph

Article in Drugs & aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 72 citations in OpenAlex.

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  3. Implementation of a deprescribing guideline by community pharmacists: A focus group study.Exploratory research in clinical and social pharmacy · 2026
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  17. Mobile applications on app stores for deprescribing: A scoping review.British journal of clinical pharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Jamila AbouDepartment of Clinical Pharmacology and Pharmacy, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands. j.abou@amsterdamumc.nl.ORCID http://orcid.org/0000-0002-6521-6203
Stijn CrutzenDepartment of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Vashti TrompDepartment of Clinical Pharmacology and Pharmacy, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands.
Mette HeringaSIR Institute for Pharmacy Practice and Policy, Theda Mansholtstraat 5B, 2331 JE, Leiden, The Netherlands.
Rob Van MarumDepartment of Elderly Care Medicine, Amsterdam Public Health Research Institute, Amsterdam UMC (location VUmc), The Netherlands.
Petra EldersDepartment of General Practice, Amsterdam UMC, location VU, Amsterdam Public Health research institute, Amsterdam, The Netherlands.
Katja TaxisUnit of PharmacoTherapy, Epidemiology and Economics, Groningen Research Institute of Pharmacy, University of Groningen, Groningen, The Netherlands.
Petra DenigDepartment of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Jacqueline HugtenburgDepartment of Clinical Pharmacology and Pharmacy, Amsterdam UMC, Location VUmc, Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLUniversity Medical Center Groningen · NLAmsterdam Neuroscience · NLAmsterdam Public Health · NLUniversity of Groningen · NLUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBenefits and risks of preventive medication change over time for ageing patients and deprescribing of medication may be needed. Deprescribing of cardiovascular and antidiabetic drugs can be challenging and is not widely implemented in daily practice.

objectiveThe aim of this study was to identify barriers and enablers of deprescribing cardiometabolic medication as seen by healthcare providers (HCPs) of different disciplines, and to explore their views on their specific roles in the process of deprescribing.

methodsThree focus groups with five general practitioners, eight pharmacists, three nurse practitioners, two geriatricians, and two elder care physicians were conducted in three cities in The Netherlands. Interviews were recorded and transcribed verbatim. Directed content analysis was performed on the basis of the Theoretical Domains Framework. Two researchers independently coded the data.

resultsMost HCPs agreed that deprescribing of cardiometabolic medication is relevant but that barriers include lack of evidence and expertise, negative beliefs and fears, poor communication and collaboration between HCPs, and lack of resources. Having a guideline was considered an enabler for the process of deprescribing of cardiometabolic medication. Some HCPs feared the consequences of discontinuing cardiovascular or antidiabetic medication, while others were not motivated to deprescribe when the patients experienced no problems with their medication. HCPs of all disciplines stated that adequate patient communication and involving the patients and relatives in the decision making enables deprescribing. Barriers to deprescribing included the use of medication initiated by specialists, the poor exchange of information, and the amount of time it takes to deprescribe cardiometabolic medication. The HCPs were uncertain about each other's roles and responsibilities. A multidisciplinary approach including the pharmacist and nurse practitioner was seen as the best way to support the process of deprescribing and address barriers related to resources.

conclusionHCPs recognized the importance of deprescribing cardiometabolic medication as a medical decision that can only be made in close cooperation with the patient. To successfully accomplish the process of deprescribing they strongly recommended a multidisciplinary approach.

Indexed as

Cardiovascular DiseasesDeprescriptionsGeneral PractitionersAgedFocus GroupsHumansPharmacists

Identifiers

PMID35187614
PMCPMC8934783
OpenAlexW4213267728

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.