Evidence map›Paper›PMID 35187590›Full record

ArticleLangenbeck's archives of surgery2022

Outcomes of patients with ischemic colitis causing severe hematochezia managed medically or surgically.

Thongsak Wongpongsalee, Usah Khrucharoen, Dennis M Jensen, Rome Jutabha, Mary Ellen Jensen, Gail Thibodeau

Abstract read
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In one paragraph

Article in Langenbeck's archives of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Ischemic colitis as a cause of severe hematochezia: A mini review.Journal of clinical and experimental gastroenterology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Thongsak WongpongsaleeCURE Hemostasis Research Unit and the UCLA Digestive Diseases Research Core Center (UCLA: DDRCC), Los Angeles, CA, USA.
Usah KhrucharoenCURE Hemostasis Research Unit and the UCLA Digestive Diseases Research Core Center (UCLA: DDRCC), Los Angeles, CA, USA.
Dennis M JensenCURE Hemostasis Research Unit and the UCLA Digestive Diseases Research Core Center (UCLA: DDRCC), Los Angeles, CA, USA. djensen@mednet.ucla.edu.
Rome JutabhaCURE Hemostasis Research Unit and the UCLA Digestive Diseases Research Core Center (UCLA: DDRCC), Los Angeles, CA, USA.
Mary Ellen JensenCURE Hemostasis Research Unit and the UCLA Digestive Diseases Research Core Center (UCLA: DDRCC), Los Angeles, CA, USA.
Gail ThibodeauCURE Hemostasis Research Unit and the UCLA Digestive Diseases Research Core Center (UCLA: DDRCC), Los Angeles, CA, USA.
VA Greater Los Angeles Healthcare System · USRonald Reagan UCLA Medical Center · USSiriraj Hospital · THUniversity of California, Los Angeles · US

Funding

Pilot and Feasibility ProgramP30DK041301 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ROZENGURT, JUAN ENRIQUE · 1990 to 2019
$18.0M
NIDDK NIH HHS P30DK41301Veterans Administration Clinical Merit Review Research Grant 5I01CX001403
6 · The paper itself

Abstract

purposeTo compare short- and long-term outcomes of hospitalized patients with ischemic colitis (IC) presenting with severe hematochezia and treated medically or colectomy and also those with inpatient vs. outpatient start of hematochezia.

methodsA retrospective analysis of prospectively collected data for IC patients hospitalized for severe hematochezia from two teaching hospitals was done from 1994 to 2020, with the diagnosis of IC made colonoscopically and confirmed histologically.

resultsNinety-seven patients initially all had medical management for IC. Seventy-two (74.2%) were stable and had no further bleeding; 17 (17.5%) had colon resection; and 8 were critically ill and not surgical candidates. Surgical patients and non-surgical candidate had higher comorbidity scores; received more red blood cell (RBC) transfusion (median (IQR) 5 (3-10) vs. 4.5 (3-6.5) vs. 1 (0-4) units, p < 0.001); had significantly longer hospital and ICU days; had higher severe complication rates (35.3% vs. 100%. vs. 5.6%, p < 0.001); and had higher 30-day all-cause mortality rates (23.5% vs. 87.5% vs. 0, p < 0.001). Inpatients developing IC hemorrhage had more RBC transfusions, more complications, longer hospital stays, and higher mortality than patients whose IC bleeding started as outpatients.

conclusionsThe majority of IC patients hospitalized for severe hematochezia were successfully treated medically. Patients who were not surgical candidate had the highest rates of severe complications and mortality. Surgical patients and those who were not surgical candidate had worse outcomes than the medical group. Patients with inpatient start of bleeding from IC had significantly worse outcomes than those with outpatient start of bleeding.

Indexed as

Colitis, IschemicGastrointestinal HemorrhageHospitalizationHumansLength of StayRetrospective StudiesClinical outcomesColectomyHematocheziaIschemic colitisLower gastrointestinal bleedingMedical management

Identifiers

PMID35187590
OpenAlexW4212848614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.