Evidence map›Paper›PMID 35187393›Full record

ArticleEuropean heart journal. Case reports2022

Intracoronary IgG4-related disease as an unusual cause of sudden cardiac arrest: a case series.

Elizabeth D Paratz, Laura Ross, Dominica Zentner, Natalie Morgan, Heinrich Bouwer, Matthew Lynch, Sarah Parsons, Andre La Gerche

Open access · goldAbstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Elizabeth D ParatzDepartment of Cardiology, Baker Heart and Diabetes Institute, 75 Commercial Road, Prahran, VIC 3181, Australia.ORCID https://orcid.org/0000-0002-2122-9889
Laura RossDepartment of Cardiology, St Vincent's Hospital Melbourne, 41 Victoria Pde, Fitzroy. VIC 3065, Australia.ORCID https://orcid.org/0000-0003-4636-729X
Dominica ZentnerDepartment of Cardiology, Royal Melbourne Hospital, 300 Grattan Street, Parkville, VIC 3050, Australia.ORCID https://orcid.org/0000-0003-0437-1581
Natalie MorganVictorian Institute of Forensic Medicine, 65 Kavanagh Street, Southbank, VIC 3006, Australia.ORCID https://orcid.org/0000-0002-8198-5723
Heinrich BouwerVictorian Institute of Forensic Medicine, 65 Kavanagh Street, Southbank, VIC 3006, Australia.
Matthew LynchVictorian Institute of Forensic Medicine, 65 Kavanagh Street, Southbank, VIC 3006, Australia.
Sarah ParsonsVictorian Institute of Forensic Medicine, 65 Kavanagh Street, Southbank, VIC 3006, Australia.ORCID https://orcid.org/0000-0002-1238-1360
Andre La GercheDepartment of Cardiology, Baker Heart and Diabetes Institute, 75 Commercial Road, Prahran, VIC 3181, Australia.ORCID https://orcid.org/0000-0002-3906-3784
Victorian Institute of Forensic Medicine · AUBaker Heart and Diabetes Institute · AUThe Royal Melbourne Hospital · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIgG4-related disease (IgG4-RD) is a fibro-inflammatory condition classically causing retroperitoneal fibrosis, aortitis, thyroiditis, or pancreatitis. Diagnosis includes the presence of lymphoplasmacytic infiltrate (with >40% ratio IgG4+:IgG plasma cells) and fibrosis. Cardiac involvement may include aortic, pericardial, or coronary disease. Coronary manifestations encompass obstructive intra-luminal lesions, external encasing pseudo-tumour on imaging, or lymphoplasmacytic arteritis. CASE SUMMARY: DISCUSSION: IgG4-related disease presenting as sudden cardiac death without any preceding symptoms is very rare (six prior cases identified on literature review). Reported targeted successful interventions for intracoronary IgG4-RD diagnosed in life have included steroid therapy and B cell depleting therapy (i.e. rituximab). If cardiac symptoms are present in a patient with known IgG4-RD, cardiac investigations should be promptly arranged.

Indexed as

Case reportCoronary artery diseaseIgG4-related diseasePost-mortemSudden cardiac death

Identifiers

PMID35187393
PMCPMC8851923
OpenAlexW4210851183

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.