Evidence map›Paper›PMID 35187160›Full record

ArticleBioMed research international2022

Analysis of the Role of Selective Neck Dissection in Clinically Node-Positive T3/T4 Oral Cancers.

Dungala Dileep Maharaj, Rajkumar Kottayasamy Seenivasagam, Kinjal Shankar Majumdar, Abhinav Thaduri, Achyuth Panuganti, Pallvi Kaul, Jarang Rajesh Kumar, Nooruddin Mohammed

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Level V Metastases in Node-Positive Oral Squamous Cell Carcinoma: Beyond Level IIA and III.ORL; journal for oto-rhino-laryngology and its related specialties · 2024
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Dungala Dileep MaharajDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, Rishikesh, India.
Rajkumar Kottayasamy SeenivasagamDepartment of Surgical Oncology, All India Institute of Medical Sciences, Rishikesh, India.ORCID https://orcid.org/0000-0002-7371-4958
Kinjal Shankar MajumdarDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, Rishikesh, India.ORCID https://orcid.org/0000-0003-4696-3139
Abhinav ThaduriDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, Rishikesh, India.
Achyuth PanugantiDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, Rishikesh, India.
Pallvi KaulDepartment of Otorhinolaryngology and Head and Neck Surgery, All India Institute of Medical Sciences, Rishikesh, India.
Jarang Rajesh KumarDepartment of General Surgery, All India Institute of Medical Sciences, Mangalagiri, India.
Nooruddin MohammedDepartment of General Surgery, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Vijayawada, India.
All India Institute of Medical Sciences Rishikesh · INAll India Institute of Medical Sciences · INSiddhartha Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe concept of selective neck dissection (SND) in locally advanced oral cancers is emerging. Contemporary studies support the feasibility of SND in selected node-positive oral cancers with early primaries. Nevertheless, the suitability of SND in clinically node-positive (cN+) oral cancers with advanced primaries (T3/T4) is unknown.

aimThis study explores if patients with cN+ advanced primaries were suitable candidates for SND by spotting the involved lymph node distribution in various stations of the neck. Secondary objectives were to check if predictive clinicopathological factors for metastases to the neck in general also apply for lymph node metastases to levels IV and V.

methodsThe present retrospective study analysed the distribution of pathologically involved lymph nodes in 134 patients and explored the interrelation of various predictive factors and cervical metastases overall and those specific to levels IV and V.

resultsLevel V was involved in 6.7% (6/83) of T4 and none of the T3 primaries. Depth of invasion (DOI), perineural invasion (PNI), and skin invasion were statistically significant predictors for nodal metastases in general on multivariate analysis.

conclusionOur analysis supports the option of considering SND, sparing level V in patients with cN+ oral cancers in a subset with T3 primary and nodal stage N2 and below.

Indexed as

AgedFemaleHumansLymphatic MetastasisLymph Node ExcisionMaleMiddle AgedMouth NeoplasmsNeck DissectionNeoplasm StagingRetrospective Studies

Identifiers

PMID35187160
PMCPMC8853780
OpenAlexW4211255420

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.