Evidence map›Paper›PMID 35187133›Full record

ArticleFrontiers in cardiovascular medicine2022

Deciphering Cell-Cell Communication in Abdominal Aortic Aneurysm From Single-Cell RNA Transcriptomic Data.

Huan Yang, Elise DeRoo, Ting Zhou, Bo Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Efferocytosis-associated Mrc1Frontiers in immunology · 2026
    Article
  3. Spatial Transcriptomics RevealsbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Single-cell transcriptomeFrontiers in cardiovascular medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Huan YangDepartment of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, United States.
Elise DeRooDepartment of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, United States.
Ting ZhouDepartment of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, United States.
Bo LiuDepartment of Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, United States.
University of Wisconsin–Madison · US

Funding

Role of RIP3-laden extracellular vesicles in thrombosis and aortic aneurysmR01HL149404 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LIU, BO · 2020 to 2023
$2.0M
Novel Role of Thrombospondin-1 in Protection against Rupture of Abdominal Aortic AneurysmR01HL158073 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI LIU, BO · 2021 to 2024
$1.9M
NHLBI NIH HHS R01 HL149404NHLBI NIH HHS R01 HL158073
6 · The paper itself

Abstract

Cell-cell communication coordinates cellular differentiation, tissue homeostasis, and immune responses in states of health and disease. In abdominal aortic aneurysm (AAA), a relatively common and potentially life-threatening vascular disease, intercellular communications between multiple cell types are not fully understood. In this study, we analyzed published single-cell RNA sequencing (scRNA-seq) datasets generated from the murine CaCl

Indexed as

abdominal aortic aneurysmanimal modelscell-cell communicationsingle-cell RNA sequencingthrombospondin

Identifiers

PMID35187133
PMCPMC8854649
OpenAlexW4210790098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.