Evidence map›Paper›PMID 35187112›Full record

ReviewFrontiers in cardiovascular medicine2021

Treatment and Outcome of Patients With Coronary Artery Ectasia: Current Evidence and Novel Opportunities for an Old Dilemma.

Luca Esposito, Marco Di Maio, Angelo Silverio, Francesco Paolo Cancro, Michele Bellino, Tiziana Attisano, Fabio Felice Tarantino, Giovanni Esposito, Carmine Vecchione, Gennaro Galasso and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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  4. Visceral Adiposity Index in Coronary Artery Ectasia.The Eurasian journal of medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Luca EspositoDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Marco Di MaioDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Angelo SilverioDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Francesco Paolo CancroDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Michele BellinoDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Tiziana AttisanoDivision of Interventional Cardiology, Cardiovascular and Thoracic Department, San Giovanni di Dio e Ruggi, Salerno, Italy.
Fabio Felice TarantinoCath Lab Unit, Cardiovascular Department, Morgagni Hospital, Vecchiazzano-Forlì, Italy.
Giovanni EspositoDepartment of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy.
Carmine VecchioneDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Gennaro GalassoDepartment of Medicine, Surgery and Dentistry, University of Salerno, Salerno, Italy.
Cesare BaldiDivision of Interventional Cardiology, Cardiovascular and Thoracic Department, San Giovanni di Dio e Ruggi, Salerno, Italy.
University of Salerno · ITNuovo Ospedale San Giovanni di Dio · ITOspedali Riuniti San Giovanni di Dio e Ruggi d'Aragona · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery ectasia (CAE) is defined as a diffuse or focal dilation of an epicardial coronary artery, which diameter exceeds by at least 1. 5 times the normal adjacent segment. The term ectasia refers to a diffuse dilation, involving more than 50% of the length of the vessel, while the term aneurysm defines a focal vessel dilation. CAE is a relatively uncommon angiographic finding and its prevalence ranges between 0.3 and 5% of patients undergoing coronary angiography. Although its pathophysiology is still unclear, atherosclerosis seems to be the underlying mechanism in most cases. The prognostic role of CAE is also controversial, but previous studies reported a high risk of cardiovascular events and mortality in these patients after percutaneous coronary intervention. Despite the availability of different options for the interventional management of patients with CAE, including covered stent implantation and stent-assisted coil embolization, there is no one standard approach, as therapy is tailored to the individual patient. The abnormal coronary dilation, often associated with high thrombus burden in the setting of acute coronary syndromes, makes the interventional treatment of CAE patients challenging and often complicated by distal thrombus embolization and stent malapposition. Moreover, the optimal antithrombotic therapy is debated and includes dual antiplatelet therapy, anticoagulation, or a combination of them. In this review we aimed to provide an overview of the pathophysiology, classification, clinical presentation, natural history, and management of patients with CAE, with a focus on the challenges for both clinical and interventional cardiologists in daily clinical practice.

Indexed as

acute coronary syndromeantithrombotic therapycoronary artery diseasecoronary artery ectasiapercutaneous coronary intervention

Identifiers

PMID35187112
PMCPMC8854288
OpenAlexW4210610619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.