Evidence map›Paper›PMID 35187109›Full record

ArticleFrontiers in cardiovascular medicine2021

The Burden of Ventricular Premature Complex Is Associated With Cardiovascular Mortality.

Po-Tseng Lee, Ting-Chun Huang, Mu-Hsiang Huang, Ling-Wei Hsu, Pei-Fang Su, Yen-Wen Liu, Meng-Hsuan Hung, Ping-Yen Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Po-Tseng LeeInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ting-Chun HuangInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Mu-Hsiang HuangDivision of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ling-Wei HsuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Pei-Fang SuDepartment of Statistics, College of Management, National Cheng Kung University, Tainan, Taiwan.
Yen-Wen LiuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Meng-Hsuan HungInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Ping-Yen LiuInstitute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
National Cheng Kung University · TWNational Cheng Kung University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVentricular premature complex (VPC) is one of the most common ventricular arrhythmias. The presence of VPC is associated with an increased risk of heart failure (HF).

methodWe designed a single-center, retrospective, and large population-based cohort to clarify the role of VPC burden in long-term prognosis in Taiwan. We analyzed the database from the National Cheng Kung University Hospital-Electronic Medical Record (NCKUH-EMR) and NCKUH-Holter (NCKUH-Holter). A total of 19,527 patients who underwent 24-h Holter ECG monitoring due to palpitation, syncope, and clinical suspicion of arrhythmias were enrolled in this study.

resultsThe clinical outcome of interests involved 5.65% noncardiovascular death and 1.53% cardiovascular-specific deaths between 2011 and 2018. Multivariate Cox regression analysis, Fine and Gray's competing risk model, and propensity score matching demonstrated that both moderate (1,000-10,000/day) and high (>10,000/day) VPC burdens contributed to cardiovascular death in comparison with a low VPC burden (<1,000/day).

conclusionA higher VPC burden

Indexed as

24-h Holter electrocardiogramcardiovascular mortalitycox regression analysisFine and Gray's modelventricular premature complex (VPC)

Identifiers

PMID35187109
PMCPMC8850345
OpenAlexW4210343258

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.