Evidence map›Paper›PMID 35186961›Full record

ArticleFrontiers in medicine2021

Extracellular Vesicles Derived From Human Corneal Endothelial Cells Inhibit Proliferation of Human Corneal Endothelial Cells.

Mohit Parekh, Hefin Rhys, Tiago Ramos, Stefano Ferrari, Sajjad Ahmad

Abstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Extracellular Vesicles for Corneal Endothelial Repair.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Exosomes in corneal diseases: advances in diagnosis and therapy.Frontiers in cell and developmental biology · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohit ParekhInstitute of Ophthalmology, Faculty of Brain Sciences, University College London, London, United Kingdom.
Hefin RhysFlow Cytometry Science Technology Platform, Francis Crick Institute, London, United Kingdom.
Tiago RamosInstitute of Ophthalmology, Faculty of Brain Sciences, University College London, London, United Kingdom.
Stefano FerrariInternational Center for Ocular Physiopathology, Fondazione Banca Degli Occhi del Veneto, Venice, Italy.
Sajjad AhmadInstitute of Ophthalmology, Faculty of Brain Sciences, University College London, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corneal endothelial cells (CEnCs) are a monolayer of hexagonal cells that are responsible for maintaining the function and transparency of the cornea. Damage or dysfunction of CEnCs could lead to blindness. Human CEnCs (HCEnCs) have shown limited proliferative capacity

Indexed as

corneacorneal endothelial cellsexosomesextracellular vesicleseye

Identifiers

PMID35186961
PMCPMC8854366

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.