Evidence map›Paper›PMID 35186803›Full record

Observational studyFrontiers in cellular and infection microbiology2022

Preliminary Identification of the Aerobic Cervicovaginal Microbiota in Mexican Women With Cervical Cancer as the First Step Towards Metagenomic Studies.

Gauddy Lizeth Manzanares-Leal, Jaime Alberto Coronel-Martínez, Miguel Rodríguez-Morales, Iván Rangel-Cuevas, Lilia Patricia Bustamante-Montes, Horacio Sandoval-Trujillo, Ninfa Ramírez-Durán

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Interactions between microbiota and cervical epithelial, immune, and mucus barrier.Frontiers in cellular and infection microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Gauddy Lizeth Manzanares-LealLaboratory of Medical and Environmental Microbiology, School of Medicine, Universidad Autonoma del Estado de Mexico, Toluca, Mexico.
Jaime Alberto Coronel-MartínezDepartments of Clinical Research and Medical Oncology, Instituto Nacional de Cancerologia, Mexico City, Mexico.
Miguel Rodríguez-MoralesGenomics Laboratory, Instituto Nacional de Cancerologia, Mexico City, Mexico.
Iván Rangel-CuevasGynecology Department, Maternal and Child Hospital, Instituto de Seguridad Social del Estado de México y Municipios, Toluca, Mexico.
Lilia Patricia Bustamante-MontesDeanship of Health Sciences, Universidad Autonoma de Guadalajara, Guadalajara, Jalisco, Mexico.
Horacio Sandoval-TrujilloDepartment of Biological Systems, Universidad Autonoma Metropolitana-Xochimilco, Mexico City, Mexico.
Ninfa Ramírez-DuránLaboratory of Medical and Environmental Microbiology, School of Medicine, Universidad Autonoma del Estado de Mexico, Toluca, Mexico.
Instituto Nacional de Cancerología · MXUniversidad Autónoma del Estado de México · MXInstituto de Salud del Estado de México · MXUniversidad Autónoma de Guadalajara · MXUniversidad Autónoma Metropolitana · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CC) is considered a public health problem. Recent studies have evaluated the possible relationship between the cervicovaginal microbiome and gynecologic cancer but have not studied the relationship between aerobic bacterial communities and neoplasia. The study aimed to identify the cultivable aerobic bacterial microbiota in women with cervical cancer as a preliminary approach to the metagenomic study of the cervicovaginal microbiome associated with cervical cancer in Mexican women. An observational cross-sectional study was conducted, including 120 women aged 21-71 years, divided into two study groups, women with locally advanced CC (n=60) and women without CC (n=60). Sociodemographic, gynecological-obstetric, sexual, and habit data were collected. Cervicovaginal samples were collected by swabbing, from which standard microbiological methods obtained culturable bacteria. The strains were genetically characterized by PCR-RFLP of the 16S

Indexed as

MicrobiotaUterine Cervical NeoplasmsAdultAgedCross-Sectional StudiesFemaleHumansMiddle AgedPregnancyRNA, Ribosomal, 16SVaginaYoung AdultRNA, Ribosomal, 16Saerobic bacteriaaerobic vaginitiscervical cancercervicovaginal microbiomehuman microbiome

Identifiers

PMID35186803
PMCPMC8847610
OpenAlexW4210565718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.