Evidence map›Paper›PMID 35186781›Full record

ArticleFrontiers in cellular and infection microbiology2021

Use of Clinical Isolates to Establish Criteria for a Mouse Model of Latent

Minna Ding, Kyle D Smith, Darin L Wiesner, Judith N Nielsen, Katrina M Jackson, Kirsten Nielsen

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Insights from Mass Spectrometry-Based Proteomics onJournal of fungi (Basel, Switzerland) · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. State of the Field: Cytotoxic Immune Cell Responses inJournal of fungi (Basel, Switzerland) · 2024
    Review
  12. Inbred Mouse Models inJournal of fungi (Basel, Switzerland) · 2024
    Review
  13. mBio · 2024
    Article
  14. Review
  15. bioRxiv : the preprint server for biology · 2023
    Article
  16. Article
  17. Importance of Clinical Isolates inJournal of fungi (Basel, Switzerland) · 2023
    Review
  18. Mouse Model of Latent Cryptococcal Infection and Reactivation.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Minna DingDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, United States.
Kyle D SmithDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, United States.
Darin L WiesnerDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, United States.
Judith N NielsenDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, United States.
Katrina M JacksonDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, United States.
Kirsten NielsenDepartment of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN, United States.
University of Minnesota Medical Center · USRutgers New Jersey Medical SchoolUniversity of North Carolina at Chapel Hill · US

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM007618 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ANDERSON, MARK S · 1985 to 2020
$29.6M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008244 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SHIMIZU, YOJI · 1988 to 2024
$13.6M
RESEARCH TRAINING IN HEMATOLOGYT32HL007899 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Jane Ellen Churpek · 1998 to 2026
$8.2M
IMMUNOLOGY TRAINING PROGRAMT32AI007313 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Carla Rothlin · 1989 to 2026
$5.7M
Impact of Cryptococcus Titan Cells on Pathogenesis.R01AI134636 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Kirsten Nielsen · 2018 to 2026
$4.6M
Genomic Research Capacity Building for Cryptococcosis Translational StudiesR01NS118538 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI Joel Bazira, David Bisagaya Meya · 2020 to 2026
$3.4M
HLA Alleles and the Progression of Human CryptococcosisR21AI150303 · NIAID · UNIVERSITY OF MINNESOTA · PI NIELSEN, KIRSTEN · 2020 to 2021
$438k
Control of cryptococcal infection through manipulation of the host immune response.R21AI122352 · NIAID · UNIVERSITY OF MINNESOTA · PI NIELSEN, KIRSTEN · 2016 to 2017
$419k
The adaptive host response to latent cryptococcosisF30AI155292 · NIAID · UNIVERSITY OF MINNESOTA · PI DING, MINNA · 2021 to 2025
$150k
Single nucleotide variations account for strain specific virulence changes in Cryptococcus neoformansF31AI148047 · NIAID · UNIVERSITY OF MINNESOTA · PI JACKSON, KATRINA M · 2019 to 2021
$95k
NCI NIH HHS P30 CA016086NHLBI NIH HHS T32 HL007899NIAID NIH HHS F30 AI155292NIAID NIH HHS F31 AI148047NIAID NIH HHS R01 AI134636NIAID NIH HHS R21 AI122352NIAID NIH HHS R21 AI150303NIAID NIH HHS T32 AI007313NIGMS NIH HHS T32 GM007618NIGMS NIH HHS T32 GM008244NINDS NIH HHS R01 NS118538
6 · The paper itself

Abstract

The mechanisms of latency in the context of

Indexed as

CryptococcosisCryptococcus neoformansHIV InfectionsAnimalsDisease Models, AnimalHumansLungMiceMice, Inbred C57BLadaptive immunitycryptococcal meningitiscryptococcosisCryptococcus neoformanslatent fungal infectionspulmonary granulomasT-cells

Identifiers

PMID35186781
PMCPMC8847453
OpenAlexW4210324805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.