Evidence map›Paper›PMID 35186727›Full record

ArticleFrontiers in oncology2022

Three-Dimensional Convolutional Neural Network-Based Prediction of Epidermal Growth Factor Receptor Expression Status in Patients With Non-Small Cell Lung Cancer.

Xuemei Huang, Yingli Sun, Mingyu Tan, Weiling Ma, Pan Gao, Lin Qi, Jinjuan Lu, Yuling Yang, Kun Wang, Wufei Chen and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
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  7. Review
  8. Article
  9. Using Vision Transformer for high robustness and generalization in predicting EGFR mutation status in lung adenocarcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Article
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  13. Review
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  15. Explainable 1-mm Peritumoral CT Radiomics forCancer control : journal of the Moffitt Cancer Center
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Xuemei HuangDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Yingli SunDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Mingyu TanDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Weiling MaDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Pan GaoDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Lin QiDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Jinjuan LuDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Yuling YangDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Kun WangDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Wufei ChenDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Liang JinDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Kaiming KuangDianei Technology, Shanghai, China.
Shaofeng DuanPrecision Health Institution, GE Healthcare, Shanghai, China.
Ming LiDepartment of Radiology, Huadong Hospital Affiliated With Fudan University, Shanghai, China.
Fudan University · CNHuadong Hospital · CNUnited Imaging Healthcare (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesEGFR testing is a mandatory step before targeted therapy for non-small cell lung cancer patients. Combining some quantifiable features to establish a predictive model of EGFR expression status, break the limitations of tissue biopsy. MATERIALS AND

methodsWe retrospectively analyzed 1074 patients of non-small cell lung cancer with complete reports of

resultsWe successfully established Model

conclusionsEither deep learning or radiomic signature-based models can provide a fairly accurate non-invasive prediction of EGFR expression status. The model combined both features effectively enhanced the performance of radiomic models and provided marginal enhancement to deep learning models. Collectively, fusion models offer a novel and more reliable way of providing the efficacy of currently developed prediction models, and have far-reaching potential for the optimization of noninvasive EGFR mutation status prediction methods.

Indexed as

deep learningEGFRmachine learningNSCLCradiogenomicstomography

Identifiers

PMID35186727
PMCPMC8848731
OpenAlexW4210700032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.