ReviewInternational journal of ophthalmology2022
Spaceflight-associated neuro-ocular syndrome: a review of potential pathogenesis and intervention.
Review in International journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 25 citations in OpenAlex.
- A moonshot for female astronaut health, a win for all astronauts and space exploration.NPJ microgravity · 2025Article
- Brains in space: impact of microgravity and cosmic radiation on the CNS during space exploration.Nature reviews. Neuroscience · 2025Review
- Evolutionary medicine and bioastronautics: an innovative approach in addressing adverse mental health effects to astronauts during long term space missions.Frontiers in physiology · 2025Article
- Aerospace medicine in China: advancements and perspectives.NPJ microgravity · 2024Review
- XR-SANS: a multi-modal framework for analyzing visual changes with extended reality (XR) in Spaceflight Associated Neuro-Ocular Syndrome (SANS).Eye (London, England) · 2024Article
- Refractive shifts in astronauts during spaceflight: mechanisms, countermeasures, and future directions for in-flight measurements.Eye (London, England) · 2024Article
- Dynamic changes in perivascular space morphology predict signs of spaceflight-associated neuro-ocular syndrome in bed rest.NPJ microgravity · 2024Article
- Navigating the Unknown: A Comprehensive Review of Spaceflight-Associated Neuro-Ocular Syndrome.Cureus · 2024Review
- Domains of life sciences in spacefaring: what, where, and how to get involved.NPJ microgravity · 2024Article
- Article
- Validation of collaborative cyberspace virtual reality oculometry enhanced with near real-time spatial audio.Scientific reports · 2023Article
- Choroidal circulation disturbance is an initial factor in outer retinal degeneration in rats under simulated weightlessness.Frontiers in physiology · 2023Article
- Identification of a novel path for cerebrospinal fluid (CSF) drainage of the human brain.PloS one · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the continuing progress in space exploration, a new and perplexing condition related to spaceflight ocular syndrome has emerged in the past four decades. National Aeronautics and Space Administration (NASA) has named this condition "spaceflight-associated neuro-ocular syndrome" (SANS). This article gives an overview of the current research about SANS and traditional Chinese medicine (TCM) by analyzing the existing publications on PubMed and CNKI and reports from NASA about SANS, summarizing the potential pathogenesis of SANS and physical interventions for treating SANS, and discussing the feasibility of treating SANS with TCM. Due to the unique characteristics of the space environment, it is infeasible to conduct large-scale human studies of SANS. SANS may be the result of the interaction of multiple factors, including inflammation and fluid displacement in the optic nerve sheath and cerebrospinal fluid. We should pay attention to SANS. Visual function is not only related to the health of astronauts but also closely related to space operations. TCM has antioxidative stress and antiapoptotic effects and is widely used for optic nerve diseases. TCM has great potential to prevent SANS.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.