Evidence map›Paper›PMID 35186695›Full record

ArticleInternational journal of ophthalmology2022

Incidence of endophthalmitis after phacoemulsification cataract surgery: a Meta-analysis.

Si-Lu Shi, Xiao-Ning Yu, Yi-Lei Cui, Si-Fan Zheng, Xing-Chao Shentu

Open access · goldAbstract read
In one paragraph

Article in International journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

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  4. Acute Post-cataract Surgery Endophthalmitis and Corneal Ulcer withJournal of research in pharmacy practice · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Si-Lu ShiEye Center of the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, Zhejiang Province, China.
Xiao-Ning YuEye Center of the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, Zhejiang Province, China.
Yi-Lei CuiEye Center of the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, Zhejiang Province, China.
Si-Fan ZhengGKT School of Medical Education, King's College London, London SE1 1UL, England, UK.
Xing-Chao ShentuEye Center of the Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, Zhejiang Province, China.
King's College London · GBSecond Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the overall endophthalmitis incidence and the effectiveness of potential prophylaxis measures following phacoemulsification cataract surgery (PCS).

methodsThe PubMed and Web of Science databases were searched from inception to April 30

resultsA total of 39 studies containing 5 878 114 eyes were included and critically appraised in the Meta-analysis. For overall incidence of endophthalmitis after PCS, the Meta-analysis yielded a pooled estimate of 0.092% (95%CI: 0.083%-0.101%). The incidence appeared to decrease with time (before 2000: 0.097%, 95%CI: 0.060%-0.135%; 2000 to 2010: 0.089%, 95%CI: 0.076%-0.101%; after 2010: 0.063%, 95%CI: 0.050%-0.077%). Compared with typical povidone-iodine solution (0.178%, 95%CI: 0.071%-0.285%) and antibiotics subconjunctival injections (0.047%, 95%CI: 0.001%-0.095%), the use of intracameral antibiotics significantly reduced the incidence of endophthalmitis after PCS (0.045%, 95%CI: 0.034%-0.055%, RR: 7.942, 95%CI: 4.510-13.985).

conclusionDue to the advancement of phacoemulsification technology and the widespread use of intracameral antibiotics, the incidence of endophthalmitis following PCS shows a decreasing trend over time. The use of intracameral antibiotics administration will significantly reduce the risk of endophthalmitis.

Indexed as

antibiotics subconjunctival injectionsendophthalmitisintracameral antibioticsMeta-analysisphacoemulsification cataract surgerytypical povidone-iodine solution

Identifiers

PMID35186695
PMCPMC8818473
OpenAlexW4210620036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.