Evidence map›Paper›PMID 35186675›Full record

ArticleMetabolites2022

Urinary Metabolomic Changes Accompanying Albuminuria Remission following Gastric Bypass Surgery for Type 2 Diabetic Kidney Disease.

William P Martin, Daniel Malmodin, Anders Pedersen, Martina Wallace, Lars Fändriks, Cristina M Aboud, Tarissa B Zanata Petry, Lívia P Cunha da Silveira, Ana C Calmon da Costa Silva, Ricardo V Cohen and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Metabolites, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01821508 (Prospective, Open,Randomized, Unicentre Study Comparing Roux-en-Y Gastric Bypass With the Best Clinical Treatment Regarding Improvement of Microvascular Complications of Type 2 Diabetes Mellitus in Obese Patients.), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01821508 nacompletednot on this map

Prospective, Open,Randomized, Unicentre Study Comparing Roux-en-Y Gastric Bypass With the Best Clinical Treatment Regarding Improvement of Microvascular Complications of Type 2 Diabetes Mellitus in Obese Patients.

TypeinterventionalSponsorHospital Alemão Oswaldo CruzRan2013 to 2021Enrolled100ConditionsComplications of Diabetes MellitusArmsClinical Treatment, Roux-En-Y gastric bypass surgery
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Obesity-related glomerulopathy: How it happens and future perspectives.Diabetic medicine : a journal of the British Diabetic Association · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Effects of Xinjiang wild cherry plum (Frontiers in nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 4 countries.

William P MartinDiabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.ORCID 0000-0001-7005-3966
Daniel MalmodinSwedish NMR Centre, University of Gothenburg, 40530 Gothenburg, Sweden.ORCID 0000-0001-8528-0141
Anders PedersenSwedish NMR Centre, University of Gothenburg, 40530 Gothenburg, Sweden.ORCID 0000-0001-8704-5129
Martina WallaceInstitute of Food and Health, School of Agriculture and Food Science, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.
Lars FändriksInstitute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, 40530 Gothenburg, Sweden.
Cristina M AboudThe Centre for Obesity and Diabetes, Oswaldo Cruz German Hospital, São Paulo 01333-010, Brazil.
Tarissa B Zanata PetryThe Centre for Obesity and Diabetes, Oswaldo Cruz German Hospital, São Paulo 01333-010, Brazil.
Lívia P Cunha da SilveiraThe Centre for Obesity and Diabetes, Oswaldo Cruz German Hospital, São Paulo 01333-010, Brazil.
Ana C Calmon da Costa SilvaThe Centre for Obesity and Diabetes, Oswaldo Cruz German Hospital, São Paulo 01333-010, Brazil.
Ricardo V CohenThe Centre for Obesity and Diabetes, Oswaldo Cruz German Hospital, São Paulo 01333-010, Brazil.ORCID 0000-0001-8779-3055
Carel W le RouxDiabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.
Neil G DochertyDiabetes Complications Research Centre, School of Medicine, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, D04 V1W8 Dublin, Ireland.
Hospital Alemão Oswaldo Cruz · BRUniversity College Dublin · IEUniversity of Gothenburg · SE

Funding

Wellcome Trust 203930
6 · The paper itself

Abstract

In the Microvascular Outcomes after Metabolic Surgery randomised clinical trial (MOMS RCT, NCT01821508), combined metabolic surgery (gastric bypass) plus medical therapy (CSM) was superior to medical therapy alone (MTA) as a means of achieving albuminuria remission at 2-year follow-up in patients with obesity and early diabetic kidney disease (DKD). In the present study, we assessed the urinary

Indexed as

albuminuriabariatric surgeryBCAAchronic kidney diseasediabetic kidney diseasegastric bypassmetabolomicsNMR spectroscopyobesitytype 2 diabetes

Identifiers

PMID35186675
PMCPMC7612403
OpenAlexW4213268935

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.